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oxolan-3-one

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Origin: China

Cas No: 22929-52-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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CAS No.: 22929-52-8 Formula: C4H6O2 Molecular Weight: 86.08920

Description

3-Oxotetrahydrofuran is a reagent in the preperation of dihydropteridinone which are orally active Polo-like kinase-2 (Plk-2) inhibitors.

Basic Info

Chemical Name	oxolan-3-one
Synonyms	tetrahydrofuran-4-one; Tetrahydrofuran-3-one; 3-ketotetrahydrofuran; Dihydrofuran-3(2H)-one; Tetrahydrofuran-3-yloxy; 3-Oxotetrahydrofuran; 3-Oxo-1,4-epoxybutane; dihydrofuran-3-one;
CAS No.	22929-52-8
Molecular Formula	C4H6O2
Molecular Weight	86.08920
PSA	26.30000
LogP	-0.02420

Properties

Safety Info

Synthesis Route

3-Hydroxytetrahydrofuran→oxolan-3-one
furan-3-ol→oxolan-3-one
2,5-Dihydrofuran→oxolan-3-one

Precursor

2,5-Dihydrofuran
furan-3-ol
methyl 4-oxooxolane-3-carboxylate
3-Hydroxytetrahydrofuran

Downstream Product

4-(2,5-dihydrofuran-3-yl)morpholine
4-(2,3-dihydrofuran-4-yl)morpholine
3-ethynyloxolan-3-ol
3-Hydroxytetrahydrofuran

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