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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
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(R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one

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Origin: China

Cas No: 444335-16-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 444335-16-4 Formula: C10H9BrFNO3 Molecular Weight: 290.08600

    Basic Info

    Chemical Name (R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
    Synonyms

    (5R)-3-(4-bromo-3-fluorophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one;

    CAS No. 444335-16-4
    Molecular Formula C10H9BrFNO3
    Molecular Weight 290.08600
    PSA 49.77000
    LogP 1.97070

    Properties

    Refractive Index 1.589

    Safety Info

    HS Code 2934999090

    Synthesis Route

    Benzyl (4-bromo-3-fluorophenyl)carbamate+(R)-(-)-Glycidyl butyrate→(R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
    (R)-3-(3-Fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one→(R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
    (S)-(+)-3-Chloro-1,2-propanediol+2-methylpropyl (4-bromo-3-fluorophenyl)carbamate→(R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one

    Precursor

    (R)-3-(3-Fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
    2-methylpropyl (4-bromo-3-fluorophenyl)carbamate
    Benzyl (4-bromo-3-fluorophenyl)carbamate
    (R)-(-)-Glycidyl butyrate

    Downstream Product

    N-[[(5S)-3-(4-bromo-3-fluorophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

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