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quinapril

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Origin: China

Cas No: 85441-61-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 85441-61-8 Formula: C25H30N2O5 Molecular Weight: 438.51600

    Basic Info

    Chemical Name quinapril
    Synonyms

    Quinaprilum [Latin];
    Quinapril (USP/INN);
    Quinazil;
    Quinaprilum;
    Accupro;
    (3S)-2-[(2S)-[[(1S)-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1;
    (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;

    CAS No. 85441-61-8
    Molecular Formula C25H30N2O5
    Molecular Weight 438.51600
    PSA 95.94000
    LogP 2.89590

    Properties

    Appearance & Physical State white solid
    Density 1.217 g/cm3
    Boiling Point 662ºC
    Melting Point 120-130ºC
    Flash Point 354.1ºC

    Safety Info

    Safety Statements S22-S24/25

    Synthesis Route

    ethyl 2-[(1-isoquinolin-2-ium-2-yl-1-oxopropan-2-yl)amino]-4-phenylbutanoatequinapril
    (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid+N-(1-ethoxycarbonyl-3-phenylpropyl)-L-alaninequinapril
    N-[(S)-(+)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alaninequinapril

    Precursor

    (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
    N-[(S)-(+)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine
    N-(1-ethoxycarbonyl-3-phenylpropyl)-L-alanine
    L-alanine acid chloride

    Downstream Product

    Ethanol
    QUINAPRILAT HYDRATE
    Quinapril Diketopiperazine

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