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Picture of Quinapril Diketopiperazine

Quinapril Diketopiperazine

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Origin: China

Cas No: 103733-49-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 103733-49-9 Formula: C25H28N2O4 Molecular Weight: 420.50100

    Description

    Quinapril derivative. ACE inhibitor.

    Basic Info

    Chemical Name Quinapril Diketopiperazine
    Synonyms

    ethyl (2S)-2-[(3S,11aS)-3-methyl-1,4-dioxo-3,6,11,11a-tetrahydropyrazino[1,2-b]isoquinolin-2-yl]-4-phenylbutanoate;

    CAS No. 103733-49-9
    Molecular Formula C25H28N2O4
    Molecular Weight 420.50100
    PSA 66.92000
    LogP 2.61090

    Properties

    Density 1.25g/cm3
    Boiling Point 644.5ºC at 760 mmHg
    Flash Point 343.6ºC
    Refractive Index 1.617
    Vapor Pressure 1.68E-16mmHg at 25°C

    Synthesis Route

    quinapril hydrochloridequinapril+Quinapril Diketopiperazine
    quinaprilQuinapril Diketopiperazine
    (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic AcidQuinapril Diketopiperazine

    Precursor

    quinapril
    (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
    (1S,2S,3S)-2-[2-(1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl] -1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid tert-butyl ester
    2-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]propanoic acid

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