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phenylephrine

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Origin: China

Cas No: 59-42-7

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 59-42-7 Formula: C9H13NO2 Molecular Weight: 167.20500

    Description

    Phenylephrine is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo. Phenylephrine can also cause a decrease in heart rate through reflex bradycardia.

    Basic Info

    Chemical Name phenylephrine
    Synonyms

    Neophryn;
    Mydfrin;
    Mesatone;
    Mesaton;
    Phenylephrine;
    Nostril;
    Mezaton;
    Adrianol;
    Isophrin;
    Prefrin;

    CAS No. 59-42-7
    Molecular Formula C9H13NO2
    Molecular Weight 167.20500
    PSA 52.49000
    LogP 1.03590

    Properties

    Density 1.159 g/cm3
    Boiling Point 341.1ºC at 760 mmHg
    Melting Point 171ºC
    Flash Point 163.4ºC
    Refractive Index -55.5 ° (C=5, 1mol/L HCl)

    Safety Info

    RTECS DO7175000
    Safety Statements 26-36-45
    Risk Statements R22

    Synthesis Route

    1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride(+)-Phenylephrine+phenylephrine
    (R)-phenylephrine-(R)-naproxenphenylephrine
    (+)-Phenylephrinephenylephrine

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed SE-30 - 1660. temperature ramp
    Other Methyl Silicone - 1660. custom temperature program

    Precursor

    3-Methoxybenzaldehyde
    9-Brom-10-azido-9.10-dihydrophenanthren
    (R)-phenylephrine-(R)-naproxen
    1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride

    Downstream Product

    phenylephrine hydrochloride
    (R)-5-(3-Hydroxyphenyl)-3-methyl-2-oxazolidinone

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