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CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl

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Origin: China

Cas No: 103733-30-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 103733-30-8 Formula: C17H18ClNO2 Molecular Weight: 303.78300

Description

Quinapril intermediate.

Basic Info

Chemical Name	CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl
Synonyms	3-Isoquinolinecarboxylic acid,1,2,3,4-tetrahydro-,phenylMethyl ester,hydrochloride,(3S); (S)-01,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid Benzyl Ester Hydrochloride; (S)-1,2,3,4-Tetra hydro-3-Isoquinoline carboxylic acid phenyl methylester hydrochloride; (S)-Benzyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride; L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID BENZYL ESTER HCL;
CAS No.	103733-30-8
Molecular Formula	C17H18ClNO2
Molecular Weight	303.78300
PSA	38.33000
LogP	3.57510

Properties

Boiling Point	411.6ºC at 760mmHg
Flash Point	202.8ºC
Vapor Pressure	5.5E-07mmHg at 25°C

Synthesis Route

benzyl bromide→CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl
Boc-(R)-1,2,3,4-tetrahydroisoquino-line-3-carboxylic acid→CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl

Precursor

Boc-(R)-1,2,3,4-tetrahydroisoquino-line-3-carboxylic acid
benzyl bromide

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