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ofloxacin

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Origin: China

Cas No: 82419-36-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 82419-36-1 Formula: C18H20FN3O4 Molecular Weight: 361.36800

Description

Fluorinated quinolone antibacterial.

Basic Info

Chemical Name	ofloxacin
Synonyms	floxin; Exocin; TARIVID; pt01; Floxal; Visren; oflx; Oflox; Floxil; Ofloxacin; hoe280;
CAS No.	82419-36-1
Molecular Formula	C18H20FN3O4
Molecular Weight	361.36800
PSA	75.01000
LogP	1.54690

Properties

Appearance & Physical State	Off-white solid
Density	1.48g/cm3
Boiling Point	571.5ºC at 760 mmHg
Melting Point	218ºC
Flash Point	299.4ºC
Refractive Index	1.669
Stability	Stable if stored as directed..
Storage Condition	2-8ºC
Vapor Pressure	6.7E-14mmHg at 25°C

Safety Info

RTECS	UU8815550
Safety Statements	S22-S24/25
HS Code	2934999090
WGK Germany	3
Risk Statements	R22; R42/43; R68; R36/37/38
Hazard Codes	Xn; Xi

Synthesis Route

1-Methylpiperazine+9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid→ofloxacin
1-Methylpiperazine+2,2'-Biquinoline→ofloxacin
diethyl [(-)-7,8-difluoro-3-methyl-2,3-dihydro-4H-[1,4]benzoxazin-4-yl]methylenemalonate→ofloxacin

Precursor

1-Methylpiperazine
9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
2,2'-Biquinoline
2,3,4,5-Tetrafluorobenzoyl chloride

Downstream Product

Levofloxacin
D-Ofloxacin
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

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