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Picture of Levofloxacin Carboxylic Acid

Levofloxacin Carboxylic Acid

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Origin: China

Cas No: 100986-89-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    636-93-1
    Other Names:
    2-Methoxy-5-nitrophenol
    MF:
    C13H9F2NO4
    EINECS No.:
    100986-89-8
    Type:
    Pharmaceutical Intermediates
    Purity:
    99.0%min
    Brand Name:
    sartort
    Model Number:
    2-Methoxy-5-nitrophenol
    Application:
    Pharm Intermediates
    Appearance:
    White Powder, White Powder

    Packaging&Delivery

    Packaging Details
    25kg/carton
    Port
    Any port in china
    Lead Time:
    Quantity(Kilograms)1 - 1>1
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 100986-89-8 Formula: C13H9F2NO4 Molecular Weight: 281.21200

    Description

    Levofloxacin intermediate.

    Basic Info

    Chemical Name Levofloxacin Carboxylic Acid
    Synonyms

    Levofloxacin carboxylic acid;
    Levofloxacin Q-Acid;

    CAS No. 100986-89-8
    Molecular Formula C13H9F2NO4
    Molecular Weight 281.21200
    PSA 68.53000
    LogP 1.93130

    Properties

    Density 1.61 g/cm3
    Boiling Point 459.2ºC at 760 mmHg
    Melting Point >280ºC (dec.)
    Flash Point 231.5ºC
    Refractive Index 1.635
    Vapor Pressure 3.14E-09mmHg at 25°C

    Safety Info

    Safety Statements 26-36
    HS Code 2934999090
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate→Levofloxacin Carboxylic Acid
    (+) ethyl 2-(2,3,4,5-tetrafluoro)benzoyl-3-[(1-acetoxy-prop-2(S)-yl)amino]acrylate+Diethyl ether→Levofloxacin Carboxylic Acid
    (-)-ethyl 1,4-dihydro-1-[1(S)-(hydroxymethyl)ethyl]-4-oxo-6,7,8-trifluoroquinoline-3-carboxylate→Levofloxacin Carboxylic Acid

    Precursor

    ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate
    (-)-ethyl 1,4-dihydro-1-[1(S)-(hydroxymethyl)ethyl]-4-oxo-6,7,8-trifluoroquinoline-3-carboxylate
    (+) ethyl 2-(2,3,4,5-tetrafluoro)benzoyl-3-[(1-acetoxy-prop-2(S)-yl)amino]acrylate
    Diethyl ether

    Downstream Product

    Levofloxacin
    S-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido-<1,2,3-de><1,4>benzoxazine-6-carboxylic acid
    Levofloxacin Hemihydrate

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