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enrofloxacin

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Origin: China

Cas No: 93106-60-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Standard: CVP/EP/USP

Certificate: CEP

Chemical name: 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolonecarboxylic acid

CAS #：93106-60-6
Molecular formula: C₁₉H₂₂FN₃O₃
Molecular weight: 359.39
Melting range: 221-226℃
Appearance：White or light yellow crystalline powder
Therapeutic category: Third generation Quinolones antibacterial products, veterinary use

Property

CAS No.: 93106-60-6 Formula: C19H22FN3O3 Molecular Weight: 359.39500

Description

Fluorinated quinolone antibacterial.

Basic Info

Chemical Name	enrofloxacin
Synonyms	bayvp2674; Enorfloxacin; Enrolfoxacin; 1-cyclopropyl-7-(4-ethyl-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid; cfpq; Enrofoxacin; Enrofloxacin; 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-ethyl-1-piperazinyl)-quinoline-3-carboxylic acid; 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; ROFLOXACIN BASE; Baytri; 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-ethyl-1-piperazinyl)-3-quinolinecarboxylic acid; 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-ethylpiperazino)-quinoline-3-carboxylic acid;
CAS No.	93106-60-6
Molecular Formula	C19H22FN3O3
Molecular Weight	359.39500
PSA	65.78000
LogP	2.31850

Properties

Appearance & Physical State	Pale Yellow Crystals
Density	1.385g/cm3
Boiling Point	560.5ºC at 760mmHg
Melting Point	221-226ºC
Flash Point	292.8ºC
Stability	Stable at normal temperatures and pressures.
Storage Condition	Keep tightly closed.

Safety Info

RTECS	VB1993650
Safety Statements	S26; S36/37
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

ditrimethylsilyl N-cyclopropyl-3-(4-ethyl-1-piperazinyl)anilinomethylenemalonate→enrofloxacin
1-Ethylpiperazine+7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid→enrofloxacin
2,4-Dichloro-5-fluorobenzoyl chloride→enrofloxacin

Precursor

ditrimethylsilyl N-cyclopropyl-3-(4-ethyl-1-piperazinyl)anilinomethylenemalonate
1-Ethylpiperazine
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
ethyl 3-(2,4-dichloro-5-fluorophenyl)-3-oxopropanoate

Downstream Product

1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoroquinolin-4-one

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