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ciprofloxacin

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Origin: China

Cas No: 85721-33-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    Standard: CP/USP/EP/BP/CVP

    Appearance：White or light yellow crystalline powder

    Therapeutic category: Wide-range antibacterial

    CAS No.:
    85721-33-1
    Other Names:
    CIPROFLOXACIN BASE
    MF:
    C17H18FN3O3
    EINECS No.:
    NA
    Place of Origin:
    Zhejiang, China
    Type:
    Antibiotic and Antimicrobial Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    AFINE
    Model Number:
    AFP0139
    Purity:
    99%min
    MOQ:
    According to regular packing
    Price:
    Negotiable & depends on quantity
    COA&Document:
    Please send us inquiry

    Packaging&Delivery

    Packaging Details
    According to regular packing.
    Port
    Shanghai or Hangzhou or Beijing etc
    Lead Time:
    Quantity(Kilograms) 1 - 1000 >1000
    Est. Time(days) 30 To be negotiated

     

     

     

  •  

    Property

    CAS No.: 85721-33-1 Formula: C17H18FN3O3 Molecular Weight: 331.34200
     

    Description

    Fluorinated quinolone antibacterial.
     

    Basic Info

    Chemical Name ciprofloxacin
    Synonyms

    CPFX;
    ciproiv;
    CIPROBAY;
    euciprin;
    Cipro;
    Ciprine;
    ciloxan;
    Ciprofloxacin;
    Cipmbay;
    ciprobid;
    Baycip;

    CAS No. 85721-33-1
    Molecular Formula C17H18FN3O3
    Molecular Weight 331.34200
    PSA 74.57000
    LogP 1.97710
     

    Properties

    Appearance & Physical State White Powder
    Density 1.461 g/cm3
    Boiling Point 581.8ºC at 760 mmHg
    Melting Point 255-257ºC
    Flash Point 305.6ºC
    Storage Condition Store at 0-5ºC
     

    Safety Info

    RTECS VB1993800
    Safety Statements S26; S36
    HS Code 3004909090
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi
     

    Synthesis Route

    piperazine+7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid→ciprofloxacin+Ciprofloxacin (hydrochloride)
    piperazine+7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid→ciprofloxacin
    piperazine+7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid→ciprofloxacin
     

    Toxicity

    Exposure RouteType of TestSpecies ObservedDose/DurationToxic Effects
    Oral TDLo - Lowest published toxic dose Human - man 21429 ug/kg/3D-I 1.Behavioral-hallucinations, distorted perceptions
    2.Behavioral-toxic psychosis
    Oral TDLo - Lowest published toxic dose Human - man 21 mg/kg/3D-I 1.Kidney, Ureter, Bladder-urine volume decreased
    2.Kidney, Ureter, Bladder-proteinuria
    3.Kidney, Ureter, Bladder-hematuria
    Oral LDLo - Lowest published lethal dose Human - man 5714 ug/kg/2D-I 1.Behavioral-coma
    2.Liver-jaundice, other or unclassified
    3.Liver-liver function tests impaired
     

    Precursor

    1-cyclopropyl-6-fluoro-4-oxo-7-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
    Dimethyl sulfoxide
    2,4,5-Trifluorobenzoyl chloride
    piperazine
     

    Downstream Product

    1-cyclopropyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
    Ciprofloxacin (hydrochloride)
    1-cyclopropyl-6-fluoro-7-piperazin-1-ylquinolin-4-one
    1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carbaldehyde

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