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D-Ofloxacin

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Origin: China

Cas No: 100986-86-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 100986-86-5 Formula: C18H20FN3O4 Molecular Weight: 361.36800

    Description

    Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin.

    Basic Info

    Chemical Name D-Ofloxacin
    Synonyms

    DR 3354;
    D-ofloaxcin;
    DEXTROFLOXACINE;
    d-isomer of ofloxacin;

    CAS No. 100986-86-5
    Molecular Formula C18H20FN3O4
    Molecular Weight 361.36800
    PSA 75.01000
    LogP 1.54690

    Properties

    Density 1.48g/cm3
    Boiling Point 571.5ºC at 760mmHg
    Flash Point 299.4ºC
    Refractive Index 1.669
    Vapor Pressure 6.7E-14mmHg at 25°C

    Safety Info

    HS Code 2934999090

    Synthesis Route

    ofloxacin→Levofloxacin+D-Ofloxacin
    1-Methylpiperazine+(R)-(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid→D-Ofloxacin
    Ethyl (2,3,4,5-Tetrafluorobenzoyl)acetate→D-Ofloxacin

    Precursor

    ofloxacin
    1-Methylpiperazine
    3-(2,3,4,5-tetrafluorophenyl)-3-oxo-2-(ethoxymethylene)-propanoic acid ethyl ester
    (R)-(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

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