Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

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Origin: China

Cas No: 68-23-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 68-23-5 Formula: C20H26O2 Molecular Weight: 298.41900

Description

Noretynodrel (INN), or norethynodrel (USAN, BAN), also known as 17α-ethinyl-δ5,10-19-nortestosterone or as 5(10)-norethisterone, is a steroidal progestin. It was introduced in 1957 in Enovid, a combination formulation of noretynodrel and mestranol, for the treatment of gynecological and menstrual disorders. A few years later, in May 1960, Enovid was also approved as the first oral contraceptive. In addition to its progestogenic effects, noretynodrel, unlike most progestins but similarly to etynodiol diacetate, also has some estrogenic properties. It has little or no androgenic action. In accordance, noretynodrel has not been found to virilize female fetuses, in contrast to most other testosterone and 19-nortestosterone progestins such as ethisterone, norethisterone, and norethisterone acetate.

Basic Info

Chemical Name	(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
Synonyms	SC-4642; 19-Norethynodrel; Enovid; Lynestrol; Norethynodrel [Progestins]; Noretynodrel; norethynodrel; Noretinodrel [DCIT]; Norethinodrel;
CAS No.	68-23-5
Molecular Formula	C20H26O2
Molecular Weight	298.41900
PSA	37.30000
LogP	3.63660

Properties

Density	1.15g/cm3
Boiling Point	441.6ºC at 760 mmHg
Melting Point	169-170ºC
Flash Point	188.2ºC
Refractive Index	1.577

Safety Info

RTECS	RC8980000
WGK Germany	3
Risk Statements	R45; R61

Synthesis Route

→(8R,9S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,4,6,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

Downstream Product

norethisterone
10β-Hydroxy Norethindrone

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