Home > Carbonyl Compounds> 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

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Origin: China

Cas No: 100492-04-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 100492-04-4 Formula: C15H6ClF3N2O3 Molecular Weight: 354.66800

Basic Info

Chemical Name	7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Synonyms	7-chloro-1-(o,p-difluorophenyl)1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro 4-oxo-1,8-naphthyridine-3-carboxylic acid; 1,8-Naphthyridine-3-carboxylicacid,7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo; 1-(2,4-difluoroanlino)-6-fluoro-7-chloro-1,4-dihydro-4-oxo-18-naphthylidine-3-carboxylic acid; 7-chloro-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; 1-(2,4-difluorophenyl)-6-fluoro-7-chloro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid;
CAS No.	100492-04-4
Molecular Formula	C15H6ClF3N2O3
Molecular Weight	354.66800
PSA	72.19000
LogP	3.15460

Synthesis Route

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate→7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
Ethyl 2,6-Dichloro-5-Fluoro-Pyridine-3-Acetoacetate→7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
ethyl (E)-2-(2,6-dichloro-5-fluoropyridine-3-carbonyl)-3-(2,4-difluoroanilino)prop-2-enoate→7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Precursor

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
2,6-Dichloro-5-fluoronicotinic acid
Ethyl 2,6-Dichloro-5-Fluoro-Pyridine-3-Acetoacetate
ethyl (E)-2-(2,6-dichloro-5-fluoropyridine-3-carbonyl)-3-(2,4-difluoroanilino)prop-2-enoate

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