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5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole

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Origin: China

Cas No: 524-81-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 524-81-2 Formula: C19H20N2 Molecular Weight: 276.37600

Description

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.

Basic Info

Chemical Name	5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
Synonyms	1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2-methyl-5-(phenylmethyl)-; Mebhidrolina [INN-Spanish]; 3-methyl-9-benzyl-1,2,3,4-tetrahydrocarboline; EINECS 208-364-4; 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole; Mebhydroline; 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol; 9-benzyl-3-methyl-1,2,3,4-tetrahydro-3-carboline; 5-Benzyl-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indol; Mebhydrolinum [INN-Latin]; Mebhydrolin; Mebhydroline [INN-French];
CAS No.	524-81-2
Molecular Formula	C19H20N2
Molecular Weight	276.37600
PSA	8.17000
LogP	3.61540

Properties

Density	1.12 g/cm3
Boiling Point	856.1ºC at 760 mmHg
Flash Point	471.6ºC
Refractive Index	1.633

Synthesis Route

benzyl chloride→5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
3-methyl-γ-carboline→5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
1-Methyl-4-piperidone+1-Benzyl-1-phenylhydrazine→5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole

Precursor

1-Methyl-4-piperidone
3-methyl-γ-carboline
1-Benzyl-1-phenylhydrazine
benzyl chloride

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