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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Respiratory system> cetirizine
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cetirizine

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Origin: China

Cas No: 83881-51-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    83881-51-0
    Other Names:
    Cetirizine
    MF:
    C21H25ClN2O3
    EINECS No.:
    N/M
    Place of Origin:
    Hubei, China (Mainland)
    Type:
    Vitamins, Amino Acids and Coenzymes
    Grade Standard:
    Food Grade, Medicine Grade, Tech Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    hengheda
    Model Number:
    Cetirizine
    Purity:
    99%min, 99% min
    Product name:
    Factory High quality &low price 99%Stock Cetirizine CAS 83881-51-0
    Appearance:
    White powder
    Function:
    pharm grade
    Grade:
    medicine grade
    COA:
    Available
    Stock:
    Available
    Assay test method:
    HPLC
    Shelf Life:
    2 Years
    Application:
    Pharmaceutical Raw Intermediates

    Packaging&Delivery

    Packaging Details
    5 grams/Al-foil bag
    10 grams/Al-foil bag
    100 grams/Al-foil bag
    1kg/Al-foil bag
    or upon customers' request.
    Port
    Main port in China
    Lead Time:
    Quantity(Grams)1 - 1>1
    Est. Time(days)7To be negotiated

  • Property

    CAS No.: 83881-51-0 Formula: C21H25ClN2O3 Molecular Weight: 388.88800

    Description

    Cetirizine (trade names Zirtec, Zyrtec, Reactine) is a second-generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria. It is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist.
    Second-generation antihistamines like cetirizine are less able to cross the blood-brain barrier and therefore have diminished effects on the central nervous system compared to first-generation drugs: for instance they are less likely to induce drowsiness or to interfere with memory formation.

    Basic Info

    Chemical Name cetirizine
    Synonyms

    vidix;
    P-071;
    Reactine;
    CERTIRIZINE 2HCL;
    Cetrizinehydrochloride;
    Zirtek;
    Formistin;
    Cetirizine;
    Zyrlex;
    Ceterizine;

    CAS No. 83881-51-0
    Molecular Formula C21H25ClN2O3
    Molecular Weight 388.88800
    PSA 53.01000
    LogP 3.02400

    Properties

    Appearance & Physical State white to off-white crystalline powder
    Density 1.237 g/cm3
    Boiling Point 542.1ºC at 760 mmHg
    Melting Point 110-115ºC
    Flash Point 281.6ºC
    Water Solubility 101 mg/L

    Safety Info

    RTECS AG0977500
    HS Code 2933599090
    WGK Germany 3

    Synthesis Route

    2-{2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy}acetaldehyde diethylacetal→cetirizine
    Cetirizine Amide→cetirizine
    2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol,hydrochloride→cetirizine

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal LDLo - Lowest published lethal dose Rodent - mouse 116 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    Sodium chloroacetate
    Cetirizine Amide
    2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol,hydrochloride
    2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethanol

    Downstream Product

    Cetirizine Dihydrochloride

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