Home > Chiral Compounds> (2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid

(2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid

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Origin: China

Cas No: 62023-59-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 62023-59-0 Formula: C18H19NO5 Molecular Weight: 329.34700

Basic Info

Chemical Name	(2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid
Synonyms	(2S,3S)-3-[(benzyloxycarbonyl) amino]-2-hydroxy-4-phenylbutanoic acid; (2S,3S)-3-(Z-amino)-2-hydroxy-4-phenylbutyric acid; (2S,3S)-N-(benzyloxycarbonyl)-3-amino-2-hydroxy-4-phenylbutanoic acid; (2 S,3 S)-3-benzyloxycarbonylamino-2-hydroxy-4-phenylbutyric acid;
CAS No.	62023-59-0
Molecular Formula	C18H19NO5
Molecular Weight	329.34700
PSA	95.86000
LogP	2.36050

Properties

Density	1.295 g/cm3
Boiling Point	581.9ºC at 760 mmHg
Flash Point	305.7ºC
Refractive Index	1.602

Synthesis Route

(2S,3S)-N-(benzyloxycarbonyl)-AHAP-(3-amino-2-hydroxy-4-phenylbutanoic acid) ethyl ester→(2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid
(2S,3S)-N-(benzyloxycarbonyl)-AHAP-(3-amino-2-hydroxy-4-phenylbutanoic acid) ethyl ester+(2R,3S)-N-(benzyloxycarbonyl)-AHAP-(3-amino-2-hydroxy-4-phenylbutanoic acid) ethyl ester→(2R,3S)-N-(benzyloxycarbonyl)-3-amino-2-hydroxy-4-phenylbutanoic acid+(2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid
(2S,3S)-3-[[(benzyloxy)carbonyl]amino]-2-hydroxy-4-phenylbutanoic acid methyl ester→(2S,3S)-2-hydroxy-4-phenyl-3-(phenylmethoxycarbonylamino)butanoic acid

Precursor

β-[[(phenylmethoxy)carbonyl]amino]-α-oxobenzenebutanoic acid ethyl ester
(2R,3S)-N-(benzyloxycarbonyl)-AHAP-(3-amino-2-hydroxy-4-phenylbutanoic acid) ethyl ester
2-ethoxy-5-phenyl-4-[[(phenylmethoxy)carbonyl]amino]-3-oxo-1-pentene
(2S,3S)-N-(benzyloxycarbonyl)-AHAP-(3-amino-2-hydroxy-4-phenylbutanoic acid) ethyl ester

Downstream Product

(2S,3S)-1,2-Epoxy-3-(Cbz-amino)-4-phenylbutane
(2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoic acid

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