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(2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid

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Origin: China

Cas No: 19728-63-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details

CAS No.:: 19728-63-3

Other Names:: N-Carbobenzyloxy-L-threonine

MF:: C12H15NO5

EINECS No.:: 19728-63-3

Place of Origin:: Shandong, China

Type:: Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates

Purity:: ≥99%

Brand Name:: FinerChem

Model Number:: 19728-63-3

Application:: White to light yellow crystal powder

Appearance:: White to light yellow crystal powder

Product name:: N-Cbz-L-Threonine

CAS:: 19728-63-3

Molecular Weight:: 253.25

Packaging&Delivery

Packaging Details: Aluminium foil bag for within 10kg, 25kg/Fiber drum, 25kg/kraft bag

Port: SHANGHAI, QINGDAO , BEIJING, SHENZHEN , DALIAN

Lead Time:

Quantity(Kilograms)	1 - 500	>500
Est. Time(days)	4	To be negotiated

Products Description

Product Name	N-Cbz-L-Threonine
CAS No.	19728-63-3
Appearance	White to light yellow crystal powder
Assay	≥99%
Capacity	2000mt/year
Min.packing	1gram
Application	Used in biochemical reagents and peptide synthesis.
Standard	Export
Brand	Finerchem
More information	Molecular Formula: C12H15NO5 Molecular Weight: 253.25 CAS Registry Number: 19728-63-3 EINECS: 243-258-1 Melting point: 100-104 ºC alpha: -4.7 º (c=4, acetic acid)

Property

CAS No.: 19728-63-3 Formula: C12H15NO5 Molecular Weight: 253.25100

Description

N-Cbz-L-threonine is an N-Cbz-protected form of L-Threonine. L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin).

Basic Info

Chemical Name	(2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid
Synonyms	cbz-L-threonine; N-Cbz-L-ThrOH; N-Carbobenzyloxy-l-threonine; N-Benzyloxycarbonyl-L-threonine; Z-L-Thr-OH; Z-L-Threonine; N-Carbobenzyloxy-L-threonine,N-Cbz-L-threonine,Z-L-Threonine; Cbz-L-Thr-OH; N-Cbz-L-threonine; N-Carbobenzoxy-L-threonine; N-Z-L-Thr-OH; (2S,3R)-2-(((Benzyloxy)carbonyl)amino)-3-hydroxybutanoic acid; Z-Thr-OH;
CAS No.	19728-63-3
Molecular Formula	C12H15NO5
Molecular Weight	253.25100
PSA	95.86000
LogP	1.13770

Properties

Appearance & Physical State	white to light yellow crystal powder powder
Density	1.309 g/cm3
Boiling Point	483.7ºC at 760 mmHg
Melting Point	100-104ºC
Flash Point	246.3ºC
Refractive Index	-4.9 ° (C=2, AcOH)
Stability	Stable under normal temperatures and pressures.
Storage Condition	-20ºC
Vapor Pressure	3.7E-11mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2924299090
WGK Germany	3
Risk Statements	R20/21/22
Hazard Codes	Xn

Synthesis Route

L-threonine+Benzyl chloroformate→(2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid
L-threonine+benzyl 4,6-dimethoxy-1,3,5-triazinyl carbonate→(2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid
(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoic acid→(2S,3R)-3-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid

Precursor

Benzyl chloroformate
benzyl 4,6-dimethoxy-1,3,5-triazinyl carbonate
benzyl phenylmethoxycarbonyl carbonate
(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoic acid

Downstream Product

Z-THR(TBU)-OTBU
O-tert-Butyl-L-threonine tert-Butyl Ester
Z-THR-OTBU
Benzyl (2R,3S)-(1-Carbamoyl-2-Hydroxypropyl)Carbamate

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