Home > Aromatic Compounds> (2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid

(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid

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Origin: China

Cas No: 2304-96-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
2304-96-3
Other Names:
Z-L-Asparagine
MF:
C12H14N2O5
EINECS No.:
218-969-5
Place of Origin:
Jiangsu, China
Purity:
BR,98%
Classification:
General Reagents
Brand Name:
NJDULY
Model Number:
AA0399
Product name:
Z-L-Asparagine
Content:
≥98.0%
Appearance:
white crystal or crystalline powder
Storage:
RT
Melting point:
143 ~ 170 ℃
The specific rotation:
+ 5.6 ~ + 7.6 °
Function:
biochemical research
Packaging&Delivery
Packaging Details
Plastic bottle: 5g / bottle
Need other packing, please contact customer service
Port
Shanghai
Lead Time:
Quantity(Pieces) 1 - 1 >1
Est. Time(days) 7 To be negotiated

Property

CAS No.: 2304-96-3 Formula: C12H14N2O5 Molecular Weight: 266.25000

Description

Nα-Cbz-L-asparagine is an N-Cbz-protected form of L-Asparagine. L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.

Basic Info

Chemical Name	(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
Synonyms	Nα-Carbobenzoxy-L-asparagine; N2-benzyloxycarbonyl-DL-asparagine; N-Benzyloxycarbonyl-L-Asparagine; N-Cbz-L-Asparagine; N-Carbobenzoxy-L-asparagine; Nα-Cbz-L-asparagine; N-Cbz-asparagine; Z-Asn-OH; Nalpha-Carbobenzoxy-L-asparagine; Nalpha-Cbz-L-asparagine; CBZ asparagine; Carbobenzyloxy-L-asparagine; benzyloxycarbonyl-L-asparagine; Z-L-Asparagine; CBZ-L-Asparagine;
CAS No.	2304-96-3
Molecular Formula	C12H14N2O5
Molecular Weight	266.25000
PSA	118.72000
LogP	1.33260

Properties

Appearance & Physical State	White solid.
Density	1.355g/cm3
Boiling Point	580.6ºC at 760mmHg
Melting Point	160-165ºC
Flash Point	304.9ºC
Refractive Index	6.3 ° (C=1.6, AcOH)
Stability	Stable under normal temperatures and pressures.
Storage Condition	0-6ºC
Vapor Pressure	2.54E-14mmHg at 25°C

Safety Info

Safety Statements	S24/25
WGK Germany	3
Risk Statements	R20/21/22
Hazard Codes	Xi

Synthesis Route

4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid→Nα-Carbobenzoxy-D-asparagine+(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
L-asparagine+Benzyl chloroformate→(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
tert-butyl (2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoate→(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid

Precursor

Benzyl chloroformate
N-benzyloxycarbonyl-D,L-asparagine methyl ester
(2S)-4-oxo-4-phenylmethoxy-2-(phenylmethoxycarbonylamino)butanoic acid
tert-butyl (2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoate

Downstream Product

(3S)-4-methoxy-4-oxo-3-(phenylmethoxycarbonylamino)butanoic acid
methyl 2-[[4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-4-methylpentanoate
Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride
Z-ASN-ONP

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