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(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid

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Origin: China

Cas No: 138812-70-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 138812-70-1 Formula: C18H19NO4 Molecular Weight: 313.34800

Basic Info

Chemical Name	(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid
Synonyms	Cbz-D-Homophe; (S)-2-benzyloxycarbonylamino-4-phenyl-butyric acid; (S)-2-Benzyloxycarbonylamino-4-phenyl-buttersaeure; (2S)-N-(benzyloxycarbonyl)benzenebutanoic acid; (S)-2-benzyloxycarbonylamino-4-phenylbutanoic acid; (R)-2-(((Benzyloxy)carbonyl)amino)-4-phenylbutanoic acid; Cbz-D-homoPhenylalanine; Cbz-L-Homophe; Z-L-Hph-OH;
CAS No.	138812-70-1
Molecular Formula	C18H19NO4
Molecular Weight	313.34800
PSA	75.63000
LogP	3.38970

Properties

Melting Point	103 - 104 °C
Storage Condition	Store at RT.

Safety Info

HS Code	2924299090

Synthesis Route

N-(Benzyloxycarbonyloxy)succinimide+D-Homophenylalanine→(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid
benzyl (R)-2,2-dimethyl-4-phenethyloxazolidine-3-carboxylate→(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid
D-Homophenylalanine+benzyl 2,5-dioxopyrrolidine-1-carboxylate→(2R)-4-phenyl-2-(phenylmethoxycarbonylamino)butanoic acid

Precursor

Iodobenzene
N-(Benzyloxycarbonyloxy)succinimide
benzyl (R)-2,2-dimethyl-4-phenethyloxazolidine-3-carboxylate
D-Homophenylalanine

Downstream Product

(S)-2-((S)-2-Benzyloxycarbonylamino-4-phenyl-butyrylamino)-3-methyl-butyric acid
((S)-1-(S)-Oxiranyl-3-phenyl-propyl)-carbamic acid benzyl ester
benzyl ((S)-1-(((S)-1-chloro-2-oxo-5-phenylpentan-3-yl)amino)-1-oxo-4-phenylbutan-2-yl)carbamate
{(1S,2R)-3-[((2R,3S)-3-Amino-2-hydroxy-5-phenyl-pentyl)-(2-trimethylsilanyl-ethoxycarbonyl)-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid tert-butyl ester

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