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4-acetamido-N-(2-aminophenyl)benzamide

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Origin: China

Cas No: 112522-64-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
112522-64-2
MF:
C15H15N3O2
Place of Origin:
Beijing, China
Purity:
≥98%(HPLC)
Classification:
Specific Reagents
Brand Name:
psaitong
Model Number:
C10057
Application:
Nucleic Acid
Usage:
Histology
Suitable for:
Etc
Packaging&Delivery
Packaging Details
25mg 100mg in glass bottle
Port
beijing
Lead Time:
Quantity(Milligrams) 1 - 5000 >5000
Est. Time(days) 14 To be negotiated

Property

CAS No.: 112522-64-2 Formula: C15H15N3O2 Molecular Weight: 269.29900

Description

Tacedinaline is a histone deacetylase (HDAC) inhibitor. Tacedinaline is an anti-cancer agent as HDAC inhibitors block angiogenesis, arrest cell growth, and lead to differentiation and apoptosis in tumor cells. Studies show Tacedinaline to be effective against acute myeloid leukemia in vitro and in vivo when used in combination with conventional anti-cancer agents.

Basic Info

Chemical Name	4-acetamido-N-(2-aminophenyl)benzamide
Synonyms	Tacedinaline; 4-Acetamido-N-(2-aminophenyl)benzamide; Goe 5549; N-acetyldinaline; Acetyldinaline; Tacedinalina;
CAS No.	112522-64-2
Molecular Formula	C15H15N3O2
Molecular Weight	269.29900
PSA	84.22000
LogP	3.20670

Properties

Appearance & Physical State	white
Density	1.322 g/cm3
Boiling Point	450.6ºC at 760 mmHg
Flash Point	226.3ºC
Refractive Index	1.707
Vapor Pressure	2.6E-08mmHg at 25°C

Safety Info

HS Code	2924299090

Synthesis Route

6-{4-[(2-(4-acetylamino-benzoylamino)-phenylcarbamoyl)oxymethyl]-2-nitro-phenoxy}-tetrahydro-2H-pyran-2-carboxylic acid→+carbon dioxide
tert-butyl (2-(4-acetamidobenzamido)phenyl)carbamate→4-acetamido-N-(2-aminophenyl)benzamide
4-acetamidobenzoic acid+1,2-phenylenediamine→4-acetamido-N-(2-aminophenyl)benzamide

Precursor

N-Boc-1,2-phenyldiamine
4-acetamidobenzoic acid
tert-butyl (2-(4-acetamidobenzamido)phenyl)carbamate
4-acetamido-N-(2-aminophenyl)benzamide trifluoroacetate salt

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