Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one

(2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one

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Origin: China

Cas No: 1253056-18-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1253056-18-6 Formula: C16H12F6N4O Molecular Weight: 390.28300

Description

3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin; a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Basic Info

Chemical Name	(2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
Synonyms	Sitagliptin impurity S; Sitagliptin Deamino Impurity 1; 3-Desamino-2,3-dehydro Sitagliptin; (E)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one; (2E)-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one;
CAS No.	1253056-18-6
Molecular Formula	C16H12F6N4O
Molecular Weight	390.28300
PSA	51.02000
LogP	2.79320

Properties

Appearance & Physical State	Off-White Waxy Solid
Soluble	DMSO (Slightly), Methanol (Slightly)

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