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Trifluoroacetophenone

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Origin: China

Cas No: 434-45-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    434-45-7
    Other Names:
    Trifluoroacetophenone
    MF:
    C8H11F3O
    EINECS No.:
    207-103-1
    Place of Origin:
    Hunan, China
    Type:
    *
    Brand Name:
    EASCHEM
    Model Number:
    ESC8H11F3O
    Appearance:
    Liquid, Liquid

    Packaging&Delivery

    Packaging Details
    Packed in plastic drum or according to customer requirements.
    Port
    Shanghai port,Shenzhen port,Changsha port
    Lead Time:
    Quantity(Kilograms)1 - 5>5
    Est. Time(days)7To be negotiated
  • Property

    CAS No.: 434-45-7 Formula: C8H5F3O Molecular Weight: 174.12000

    Description

    2,2,2-Trifluoroacetophenone is a fluorinated acetophenone with inhibitory activity of acetylcholinesterase. 2,2,2-Trifluoroacetophenone was shown to have neuroprotective activity by inhibiting apoptosis in cerebellar granule neurons.

    Basic Info

    Chemical Name Trifluoroacetophenone
    Synonyms

    2,2,2-trifluroacetophenone;
    Ethanone, 2,2,2-trifluoro-1-phenyl-;
    2,2,2-Trifluoro-1-Phenylethanone;
    PHENYL TRIFLUOROMETHYL KETONE;
    TRIFLUOROACETYLBENZENE;
    2,2,2-TRIFLUOROACETOPHENONE;
    trifluoromethylphenyl ketone;
    2,2,2-Trifluoro-1-phenyl-ethanone;
    alpha,alpha,alpha-Trifluoroacetophenone;
    A,A,A-TRIFLUOROACETOPHENONE;

    CAS No. 434-45-7
    Molecular Formula C8H5F3O
    Molecular Weight 174.12000
    PSA 17.07000
    LogP 2.43160

    Properties

    Appearance & Physical State clear colorless to yellow liquid
    Density 1.24
    Boiling Point 165-166ºC
    Melting Point -40ºC
    Flash Point 41ºC
    Refractive Index 1.458-1.46
    Water Solubility PRACTICALLY INSOLUBLE
    Stability Stable under normal temperatures and pressures.
    Storage Condition Flammables area
    Vapor Pressure 1.72mmHg at 25°C

    Safety Info

    Hazard Class 3
    Safety Statements S16-S26-S37/39
    HS Code 29147090
    WGK Germany 3
    Packing Group III
    RIDADR UN 1224
    Risk Statements R10; R36/37/38
    Hazard Codes Xi

    Synthesis Route

    Methyl trifluoroacetate+phenyllithiumTrifluoroacetophenone+1-PHENYL-2,2,2-TRIFLUOROETHANOL
    Methyl trifluoroacetate+phenyllithiumTrifluoroacetophenone+2,2,2-trifluoro-1,1-diphenylethanol
    Benzoyl chlorideTrifluoroacetophenone+Benzoyl Fluoride

    Precursor

    2,2,2-trifluoroacetonitrile
    methyl benzoate
    fluoroform
    Benzene

    Downstream Product

    (R)-(-)-α-(TRIFLUOROMETHYL)BENZYL ALCOHOL
    (S)-(+)-α-(TRIFLUOROMETHYL)BENZYL ALCOHOL
    1-(4-chlorophenyl)-2,2,2-trifluoroethanone
    1-(3-chlorophenyl)-2,2,2-trifluoroethanone

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