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2',4',5'-Trifluoroacetophenone

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Origin: China

Cas No: 129322-83-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 129322-83-4 Formula: C8H5F3O Molecular Weight: 174.12000

Description

2,4,5-Trifluoroacetophenone is a reagent in the preparation of indazolylpyrazolopyrimidines as type I B-Raf inhibitors with antitumor activity.

Basic Info

Chemical Name	2',4',5'-Trifluoroacetophenone
Synonyms	1-(2,4,5-trifluorophenyl)ethanone;
CAS No.	129322-83-4
Molecular Formula	C8H5F3O
Molecular Weight	174.12000
PSA	17.07000
LogP	2.30650

Properties

Appearance & Physical State	Clear yellow liquid
Density	1.331
Boiling Point	199.8ºC at 760 mmHg
Melting Point	-7ºC
Flash Point	71ºC
Refractive Index	1.472
Vapor Pressure	0.335mmHg at 25°C

Safety Info

Safety Statements	S26-S36/37/39
HS Code	2914700090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

1,2,4-Trifluorobenzene+acetyl chloride→2',4',5'-Trifluoroacetophenone

Precursor

acetyl chloride
1,2,4-Trifluorobenzene

Downstream Product

1-(2,4-difluorophenyl)-6,7-difluoro-4-oxoquinoline-3-carboxylic acid
2,4,5-Trifluorobenzoyl chloride
Ethyl 2,4,5-trifluorobenzoylacetate
2,4,5-Trifluorobenzoic acid

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