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trans-4-Cyclohexyl-L-proline

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Origin: China

Cas No: 103201-78-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 103201-78-1 Formula: C11H19NO2 Molecular Weight: 197.27400

Basic Info

Chemical Name	trans-4-Cyclohexyl-L-proline
Synonyms	(2S,4S)-4-cyclohexylpyrrolidine-2-carboxylic acid; Trans-4-Cyclohexyl-L-Proline;
CAS No.	103201-78-1
Molecular Formula	C11H19NO2
Molecular Weight	197.27400
PSA	49.33000
LogP	1.95820

Properties

Density	1.114 g/cm3
Boiling Point	343.919ºC at 760 mmHg
Flash Point	161.797ºC
Refractive Index	1.517
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

(2S,4S)-1-((benzyloxy)carbonyl)-4-cyclohexylpyrrolidine-2-carboxylic acid→trans-4-Cyclohexyl-L-proline
benzyl trans-4-cyclohexyl-5-thio-N-benzyl-L-pyroglutamate→trans-4-Cyclohexyl-L-proline
((2S,4S)-4-cyclohexylpyrrolidin-2-yl)methanol→trans-4-Cyclohexyl-L-proline

Precursor

(2S,4S)-1-((benzyloxy)carbonyl)-4-cyclohexylpyrrolidine-2-carboxylic acid
3-Bromocyclohexene
L-Pyroglutaminol
benzyl trans-4-cyclohexyl-5-thio-N-benzyl-L-pyroglutamate

Downstream Product

fosinoprilat

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