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cis-4-hydroxy-L-proline

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Origin: China

Cas No: 618-27-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
618-27-9
Other Names:
cis-4-hydroxy-L-proline
MF:
C5H9NO3
EINECS No.:
N/A
Place of Origin:
Anhui, China
Type:
Anesthetic Agents, Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Antidote, Antineoplastic Agents, Antiparasitic Agents, Antipyretic Analgesics and NSAIDs, Blood System Agents, Cardiovascular Agents, Disinfectant and Preservatives, Electrolyte Balance and Dialysis Agents, Gastrointestinal Agents, Endocrine System Agents, Immune Function Agents, Respiratory System Agents, Urinary System Agents, Vitamins, Amino Acids and Coenzymes, Central Nervous System Agents, Auxiliaries and Other Medicinal Chemicals
Grade Standard:
Cosmetic Grade, Feed Grade, Food Grade, Medicine Grade, Tech Grade
Usage:
Animal Pharmaceuticals
Brand Name:
Milliflux
Model Number:
API
Purity:
99%
Shelf life:
2 Years Proper Storage
Package:
1kg/bag 25kg/drum
Test Method:
HPLC TLC UV
Storage:
Cool Dried Storage
MOQ:
1 KG
Delivery:
7 Working Days
Packaging&Delivery
Packaging Details
Customer's request
Port
Any port in china
Lead Time:
Quantity(Boxes) 1 - 1 >1
Est. Time(days) 14 To be negotiated

Property

CAS No.: 618-27-9 Formula: C5H9NO3 Molecular Weight: 131.13000

Description

Hydroxyprolines are valuable chiral building blocks for organic synthesis of pharmaceuticals. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.

Basic Info

Chemical Name	cis-4-hydroxy-L-proline
Synonyms	L-Proline, 4-hydroxy-, cis-; (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid; cis-4-Hydroxy-L-proline;
CAS No.	618-27-9
Molecular Formula	C5H9NO3
Molecular Weight	131.13000
PSA	69.56000
LogP	-0.87740

Properties

Appearance & Physical State	White solid.
Density	1.395 g/cm3
Boiling Point	355.2ºC at 760 mmHg
Melting Point	257ºC
Flash Point	168.6ºC
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at RT.

Safety Info

Safety Statements	S24/25
HS Code	2933990090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid→cis-4-hydroxy-L-proline
dibenzyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate→cis-4-hydroxy-L-proline
L-proline→cis-4-hydroxy-L-proline

Precursor

L-proline
(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
4-hydroxy-L-proline
N-Cbz-Hydroxy-L-proline

Downstream Product

(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
N-BOC-cis-4-Hydroxy-L-proline
(4S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-hydroxy-L-proline
(2S,4S)-4-FLUORO-PYRROLIDINE-2-CARBOXYLIC ACID

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