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TRANS-3-HYDROXY-L-PROLINE

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Origin: China

Cas No: 4298-08-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 4298-08-2 Formula: C5H9NO3 Molecular Weight: 131.13000

    Description

    trans-3-Hydroxyproline, is a versatile building block, used in the synthesis of various pharmaceutical and biologically active compounds. It is used as an intermediate in the synthesis of ferrocene-hydroxyproline amino acid conjugates.

    Basic Info

    Chemical Name TRANS-3-HYDROXY-L-PROLINE
    Synonyms

    3-(R)-hydroxy-2-(S)-proline;
    trans-3-hydroxy-(S)-proline;
    trans-3-Hydroxy-prolin;
    (2S,3S)-3-hydroxyproline;
    L-3-HYDROXYPROLINE;
    3(S)-trans-hydroxy-L-proline;
    H-3-HYP-OH;
    TRANS-3-HYDROXY-L-PR;
    L-3-TRANS-HYDROXYPROLINE;
    trans-3-Hydroxy-L-proline;
    L-trans-3-hydroxyproline;
    trans-3-Hydroxyproline;
    (2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid;
    H-HYP(3)-OH;
    H-PRO(3-HYDROXY)-OH;
    (3S)-3-Hydroxy-L-proline;
    3-Hydroxy-L-proline;

    CAS No. 4298-08-2
    Molecular Formula C5H9NO3
    Molecular Weight 131.13000
    PSA 69.56000
    LogP -0.87740

    Properties

    Appearance & Physical State White to light beige powder
    Density 1.395g/cm3
    Boiling Point 355.2ºC at 760mmHg
    Melting Point 235ºC
    Flash Point 168.6ºC
    Refractive Index 1.54

    Safety Info

    Safety Statements S22-S24/25
    HS Code 2933990090

    Synthesis Route

    (2S,3S)-N-benzyl-2-hydroxyprolineTRANS-3-HYDROXY-L-PROLINE
    potassium (2S,3S)-2-amino-3-hydroxy-5,5-dimethoxypentanoateTRANS-3-HYDROXY-L-PROLINE
    L-prolineTRANS-3-HYDROXY-L-PROLINE

    Precursor

    L-proline
    potassium (2S,3S)-2-amino-3-hydroxy-5,5-dimethoxypentanoate
    methyl (2S,3S)-3-hydroxy-2-[(9-phenyl-9-fluorenyl)-amino]-4-pentenoate
    (2S,3S)-N-benzyl-2-hydroxyproline

    Downstream Product

    1-O-tert-butyl 2-O-methyl (2S,3S)-3-hydroxypyrrolidine-1,2-dicarboxylate
    (2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
    (2S,3R)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
    Fmoc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid

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