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trans-3-Phenyl-L-proline

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Origem: China

Cas No: 118758-48-8

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

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CAS No.: 118758-48-8 Formula: C11H13NO2 Molecular Weight: 191.22600

Basic Info

Chemical Name	trans-3-Phenyl-L-proline
Synonyms	(2S,3R)-3-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID; 3-Phenyl-L-Proline;
CAS No.	118758-48-8
Molecular Formula	C11H13NO2
Molecular Weight	191.22600
PSA	49.33000
LogP	1.54550

Properties

Appearance & Physical State	white to off-white powder
Density	1.186g/cm3
Boiling Point	372.8ºC at 760mmHg
Melting Point	234-236ºC
Flash Point	179.3ºC
Refractive Index	1.562
Vapor Pressure	3.22E-06mmHg at 25°C

Safety Info

Safety Statements	37/39-26
HS Code	2933990090
Risk Statements	R36/37/38
Hazard Codes	Xn

Synthesis Route

methyl (2S,3R)-N-(tert-butoxycarbonyl)-β-phenylprolinate→trans-3-Phenyl-L-proline
4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one→trans-3-Phenyl-L-proline
tert-butyl (2S,3R)-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate→trans-3-Phenyl-L-proline

Precursor

4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one
cinnamaldehyde
tert-butyl (2S,3R)-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate
methyl (2S,3R)-N-(tert-butoxycarbonyl)-β-phenylprolinate

Downstream Product

(3R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-phenyl-L-proline

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