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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Brain and nervous system> Tonazocine
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Tonazocine

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Origin: China

Cas No: 71461-18-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 71461-18-2 Formula: C23H35NO2 Molecular Weight: 357.53000

    Description

    Tonazocine (WIN-42,156) is an opioid analgesic of the benzomorphan family which made it to phase II clinical trials for the treatment of postoperative pain, but development was apparently ceased and ultimately it was never marketed. Tonazocine is a partial agonist at both the mu-opioid and delta-opioid receptors, but acting more like an antagonist at the former and more like an agonist at the latter. It lacks most of the side effects of other opioids such as adverse effects on the cardiovascular system and respiratory depression, but it can cause sedation (although to a lesser degree of typical opioids), and in some patients it may induce hallucinations (probably via binding to and activating the κ-opioid receptor).

    Basic Info

    Chemical Name Tonazocine
    Synonyms

    CAS No. 71461-18-2
    Molecular Formula C23H35NO2
    Molecular Weight 357.53000
    PSA 40.54000
    LogP 4.78390

    Properties

    Density 1.03g/cm3
    Boiling Point 479.3ºC at 760 mmHg
    Flash Point 243.7ºC
    Refractive Index 1.528

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