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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Brain and nervous system> benzocaine
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benzocaine

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Origin: China

Cas No: 94-09-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 94-09-7 Formula: C9H11NO2 Molecular Weight: 165.18900

    Description

    Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is also combined with antipyrine to form A/B otic drops to relieve ear pain and remove earwax.

    Basic Info

    Chemical Name benzocaine
    Synonyms

    ORTHESIN;
    Ora-jel;
    p-aminobenzoic acid ethyl ester;
    Benzocaine;
    Anaesthin;
    Ethoform;
    Euphagin;
    ethyl 4-amino-benzoate;
    Topcaine;
    Solu H;
    ethyl ester of p-aminobenzoic acid;
    4-amino-benzoic acid ethyl ester;
    Norcaine;
    4-ethoxycarbonylaniline;
    AETHOFORM;
    ethyl 4-aminobenzene carboxylate;
    Benzoic acid, 4-amino-, ethyl ester;
    Norcain;

    CAS No. 94-09-7
    Molecular Formula C9H11NO2
    Molecular Weight 165.18900
    PSA 52.32000
    LogP 2.02670

    Properties

    Appearance & Physical State White crystalline powder
    Density 1.17
    Boiling Point 172ºC (17 torr)
    Melting Point 89-92ºC
    Flash Point > 110ºC
    Refractive Index 1.5502
    Stability Stable. Combustible. Incompatible with strong oxidizing agents.
    Storage Condition 0-6ºC

    Safety Info

    RTECS DG2450000
    Safety Statements S22; S24/25; S37/39; S26; S24
    HS Code 2922499990
    WGK Germany 2
    Packing Group III
    Risk Statements R36/37/38; R43
    Hazard Codes Xi

    Synthesis Route

    Ethyl 4-bromobenzoate→ethyl 4-[2-(4-ethoxycarbonylphenyl)iminohydrazinyl]benzoate+Diethyl 4,4'-Biphenyldicarboxylate
    ethyl 4-(3-acetyl-3-methyltriaz-1-en-1-yl)benzoate→N-methylacetamide+ethyl 4-[2-(4-ethoxycarbonylphenyl)iminohydrazinyl]benzoate
    4-{[(4-bromo-phenyl)-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-methyl]-amino}-benzoic acid ethyl ester→4-Bromobenzaldehyde+benzocaine

    Precursor

    Ethanol
    4-azido-benzoic acid ethyl ester
    Ethyl 4-iodobenzoate
    4-aminobenzoic acid

    Downstream Product

    2-methyl-4-oxo-1H-quinoline-6-carboxylic acid
    ethyl 4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoate
    ETHYL 4-PHENYLSULFANYLBENZOATE
    (2-Amino-1,3-benzothiazol-6-yl)methanol

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