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(S)-adrenaline

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Origin: China

Cas No: 150-05-0

Specification: 99%min

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 150-05-0 Formula: C9H13NO3 Molecular Weight: 183.20400

    Description

    D-(+)-Epinephrine, is an isomer of L-(-)-Epinephrine, is a hormone and a neurotransmitter. It is a Principal sympathomimetic hormone produced by the adrenal medulla. a Bronchodilator, cardiostimulant, mydriatic, and antiglaucoma.

    Basic Info

    Chemical Name (S)-adrenaline
    Synonyms

    1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, (S)-;
    4-[(1S)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol;
    (+)-epinephrine;
    (3,4-dihydroxyphenyl)-1-hydroxy-2-methylaminoethan;

    CAS No. 150-05-0
    Molecular Formula C9H13NO3
    Molecular Weight 183.20400
    PSA 72.72000
    LogP 0.74150

    Properties

    Density 1.283g/cm3
    Boiling Point 413.1ºC at 760mmHg
    Flash Point 207.9ºC
    Refractive Index 1.607
    Vapor Pressure 1.45E-07mmHg at 25°C

    Synthesis Route

    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-hydroxy-methylamido-ethan→(S)-adrenaline
    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-oxo-2-methylamido-ethan→(S)-adrenaline
    1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanone,hydrochloride→(S)-adrenaline

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Subcutaneous LDLo - Lowest published lethal dose Rodent - rat 80 mg/kg 1.Behavioral-muscle weakness
    2.Lungs, Thorax, or Respiration-acute pulmonary edema
    3.Lungs, Thorax, or Respiration-dyspnea
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 800 ug/kg 1.Behavioral-somnolence (general depressed activity)
    2.Behavioral-muscle weakness
    3.Lungs, Thorax, or Respiration-dyspnea
    Subcutaneous LD50 - Lethal dose, 50 percent kill Rodent - mouse 22530 ug/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-oxo-2-methylamido-ethan
    2,3-dihydroxybutanedioic acid
    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-hydroxy-methylamido-ethan
    1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanone,hydrochloride

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