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(R)-noradrenaline

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Origem: China

Cas No: 51-41-2

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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  • Descrição do produto
  • Property

    CAS No.: 51-41-2 Formula: C8H11NO3 Molecular Weight: 169.17800

    Description

    Norepinephrine, also known as noradrenaline, is a medication used to treat people with very low blood pressure. It is manufactured with the same formulation as the hormone and neurotransmitter norepinephrine. It is given intravenously.
    At high doses, and especially when it is combined with other vasopressors, it can lead to limb ischemia and limb death.

    Basic Info

    Chemical Name (R)-noradrenaline
    Synonyms

    (−)-Norepinephrine;
    L-Noradrenaline;
    Norepinephrine;
    1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-;

    CAS No. 51-41-2
    Molecular Formula C8H11NO3
    Molecular Weight 169.17800
    PSA 86.71000
    LogP 0.79020

    Properties

    Appearance & Physical State crystalline
    Density 1.397 g/cm3
    Boiling Point 442.6ºC at 760 mmHg
    Melting Point 220ºC
    Flash Point 221.5ºC
    Refractive Index 1.66
    Stability Stable, but may be light-sensitive. Incompatible with acids, bases, oxidizing agents. Store at -20ºC.
    Storage Condition 2-8ºC

    Safety Info

    RTECS DN5950000
    Hazard Class 6.1
    Safety Statements S28-S36/37-S45
    HS Code 2922509090
    Packing Group II
    WGK Germany 3
    RIDADR UN 2811
    Risk Statements R26/27/28
    Hazard Codes T+

    Synthesis Route

    Glycine+3,4-dihydroxybenzaldehyde(R)-noradrenaline+(S)-4-(2-amino-1-hydroxyethyl)pyrocatechol
    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-hydroxy-2-amido-ethan(R)-noradrenaline
    noradrenaline(R)-noradrenaline

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 100 ug/kg 1.Behavioral-somnolence (general depressed activity)
    2.Behavioral-muscle weakness
    3.Lungs, Thorax, or Respiration-dyspnea
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse 20 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 6 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    Glycine
    R,S-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-N,N'-1-(3,4-dihydroxyphenyl)-1-hydroxy-2-amido-ethan
    noradrenaline
    3,4-dihydroxybenzaldehyde

    Downstream Product

    1,2,3,4-tetrahydroisoquinoline-4,6,7-triol,hydrochloride
    3-hydroxy-2,3-dihydro-1H-indole-5,6-dione

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