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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Brain and nervous system> propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
Picture of propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate

propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate

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Origin: China

Cas No: 1421-14-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1421-14-3 Formula: C18H27NO5 Molecular Weight: 337.41100

    Description

    Sombrevin, is an ultra short-acting phenylacetate general anesthetic.

    Basic Info

    Chemical Name propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
    Synonyms

    Fabontal;
    propanidide;
    Propantan;
    Propanidid;
    Bayer 1420;
    Epontol;
    Benzeneacetic acid, 4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester;
    Fabantol;
    Sombrevin;

    CAS No. 1421-14-3
    Molecular Formula C18H27NO5
    Molecular Weight 337.41100
    PSA 65.07000
    LogP 2.43810

    Properties

    Density 1.087g/cm3
    Boiling Point 459.7ºC at 760mmHg
    Flash Point 231.8ºC
    Refractive Index 1.503
    Vapor Pressure 1.24E-08mmHg at 25°C

    Safety Info

    HS Code 2924299090

    Synthesis Route

    propyl 2-(4-hydroxy-3-methoxyphenyl)acetate+CDEA→propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous TDLo - Lowest published toxic dose Human 5 mg/kg 1.Behavioral-general anesthetic
    2.Biochemical-Metabolism (Intermediary)-histamines (including liberation not immunochemical in origin)
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat >10 gm/kg 1.Details of toxic effects not reported other than lethal dose value
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 81 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    CDEA
    propyl 2-(4-hydroxy-3-methoxyphenyl)acetate

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