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methyl (2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate

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Origin: China

Cas No: 35909-92-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 35909-92-3 Formula: C18H19NO4 Molecular Weight: 313.34800

Basic Info

Chemical Name	methyl (2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
Synonyms	N-Benzyloxycarbonylphenylalanine methyl ester; Z-L-phenylalanine methyl ester; Cbz-L-Phe-OMe; cbz-L-Phenylalanine methyl ester; N-benzyloxycarbonyl-DL-phenylalanine methyl ester; N-Benzyloxycarbonyl-L-phenylalanine methyl ester; Z-Phe-ome; L-N-(benzyloxycarbonyl)phenylalanine methyl ester; L-Phenylalanine,N-((phenylmethoxy)carbonyl)-,methyl ester; N-Cbz-L-phenylalanine methyl ester; methyl (S)-2-benzyloxycarbonylamino-3-phenylpropanoate;
CAS No.	35909-92-3
Molecular Formula	C18H19NO4
Molecular Weight	313.34800
PSA	64.63000
LogP	3.08800

Properties

Density	1.181g/cm3
Boiling Point	478.5ºC at 760mmHg
Flash Point	243.2ºC
Refractive Index	1.562
Storage Condition	-15ºC

Safety Info

HS Code	2924299090

Synthesis Route

Methanol+N-Methyl-N-nitrosotoluene-4-sulphonamide→(S)-3-Z-AMINO-1-DIAZO-3-PHENYL-2-BUTANONE+methyl (2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
diazomethane+N-Cbz-L-Phenylalanine→4-benzyl-2-phenylmethoxy-4H-1,3-oxazol-5-one+(S)-3-Z-AMINO-1-DIAZO-3-PHENYL-2-BUTANONE
diazomethane+(S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanoic (ethyl carbonic) anhydride→(S)-3-Z-AMINO-1-DIAZO-3-PHENYL-2-BUTANONE+methyl (2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate

Precursor

Benzyl chloroformate
L-Phenylalanine methyl ester hydrochloride
methyl L-phenylalaninate
N-Cbz-L-Phenylalanine

Downstream Product

(3S)-4-methoxy-4-oxo-3-(phenylmethoxycarbonylamino)butanoic acid
Methyl N-acetyl-L-phenylalaninate
N-Carbobenzoxy-DL-Phenylalanine
methyl L-phenylalaninate

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