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methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate

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Origin: China

Cas No: 1872-59-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 1872-59-9 Formula: C16H23NO5 Molecular Weight: 309.35800

Basic Info

Chemical Name	methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate
Synonyms	O-tert-Butyl-N-carbobenzoxy-L-serine Methyl Ester; N-benzyloxycarbonyl-O-t-butyl-L-serine methyl ester; Z-O-tert.butyl-L-serine methyl ester; O-(1,1-Dimethylethyl)-N-[(Phenylmethoxy)Carbonyl]-L-Serine Methyl Ester; O-tert-Butyl-N-Cbz-L-serine Methyl Ester; (S)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoate;
CAS No.	1872-59-9
Molecular Formula	C16H23NO5
Molecular Weight	309.35800
PSA	73.86000
LogP	2.66040

Properties

Density	1.117g/cm3
Boiling Point	437.2ºC at 760 mmHg
Melting Point	43ºC
Flash Point	218.2ºC
Refractive Index	6 ° (C=2, EtOH)
Vapor Pressure	7.59E-08mmHg at 25°C

Safety Info

Safety Statements	S22; S36/37/39
HS Code	2924299090
Risk Statements	R20/21/22
Hazard Codes	Xi

Synthesis Route

N-Z-L-serine methyl ester+tert-butanol→methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate
N-Z-L-serine methyl ester+Isobutene→methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate
Benzyl chloroformate→methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate

Precursor

Benzyl chloroformate
7-AMINOHEPTANOICACIDHYDROCHLORIDE
N-Z-L-serine methyl ester
tert-butanol

Downstream Product

(2R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoic acid
N-Cbz-O-tert-butyl-L-serine
(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid
Z-N-ME-SER(TBU)-OH DCHA

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