Home > Chiral Compounds> benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate

benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate

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Origin: China

Cas No: 21209-51-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
21209-51-8
Other Names:
N-Cbz-L-serine benzyl ester
MF:
C18H19NO5
EINECS No.:
N/A
Place of Origin:
Hubei, China
Type:
Amino acid intermediate
Purity:
99%min
Brand Name:
Watsonbiotech
Model Number:
Watson
Application:
Amino acid intermediate
Appearance:
white powder
Melting point:
83-86 °C
Packaging&Delivery
Packaging Details
N-Cbz-L-serine benzyl ester/Z-Ser-Obzl Cas21209-51-8
1g/bag,10g/bag, or as you require

Property

CAS No.: 21209-51-8 Formula: C18H19NO5 Molecular Weight: 329.34700

Description

N-(Benzyloxycarbonyl)serine Benzyl Ester is an intermediate in the synthesis of L-O-Phosphoserine, the catalytic domain of human protein kinase C β II when complexed with a malemide inhibitor.

Basic Info

Chemical Name	benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate
Synonyms	N-(Benzyloxycarbonyl)-L-serine benzyl ester; Cbz-Ser(Bn)-OH; (S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate; phenylmethyl (2S)-3-hydroxy-2-[(phenylmethoxy)carbonylamino]propanoate; Z-L-Ser-OBn; N-Z-serine benzyl ester; N-Z-L-Serine benzyl ester; N-Carbobenzoxy-L-serine Benzyl Ester; N-Z-L-Ser-OBn; Z-SER-OBZL; Cbz-Ser-OBzl; N-Z-L-Ser benzyl ester; N-Cbz-L-serine benzyl ester; N-Cbz-Ser-OBn; N-Benzyloxycarbonyl-L-serine benzyl ester; Z-L-serine benzyl ester;
CAS No.	21209-51-8
Molecular Formula	C18H19NO5
Molecular Weight	329.34700
PSA	84.86000
LogP	2.40800

Properties

Density	1.253g/cm3
Boiling Point	534.5ºC at 760mmHg
Melting Point	83-86ºC
Flash Point	277ºC
Refractive Index	1.58
Storage Condition	Store at RT.
Vapor Pressure	2.97E-12mmHg at 25°C

Safety Info

HS Code	2924299090
WGK Germany	3

Synthesis Route

N-Cbz-L-Serine+benzyl bromide→benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate
TosOH*Ser-OBzl+Benzyl chloroformate→benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate
N-Cbz-L-Serine→benzyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate

Precursor

Benzyl chloroformate
N-Cbz-L-Serine
benzyl chloride
benzyl bromide

Downstream Product

N-Cbz-L-Serine
benzyl (2R)-3-chloro-2-(phenylmethoxycarbonylamino)propanoate
benzyl N-[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamate

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