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(2,5-dioxopyrrolidin-1-yl) 3-phenyl-2-(phenylmethoxycarbonylamino)propanoate

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Origin: China

Cas No: 3397-32-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 3397-32-8 Formula: C21H20N2O6 Molecular Weight: 396.39300

Basic Info

Chemical Name	(2,5-dioxopyrrolidin-1-yl) 3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
Synonyms	Z-L-Phe-OH N-succinimidyl ester; Cbz-L-Phe-OSuc; Z-L-Phe-OSu; Cbz-L-Phe-OSu; EINECS 222-254-3; Z-Phe-ONSu;
CAS No.	3397-32-8
Molecular Formula	C21H20N2O6
Molecular Weight	396.39300
PSA	102.01000
LogP	2.46010

Properties

Density	1.35g/cm3
Refractive Index	1.617
Storage Condition	-15ºC

Synthesis Route

N-Hydroxysuccinimide+N-Cbz-L-Phenylalanine→(2,5-dioxopyrrolidin-1-yl) 3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
N-Cbz-L-Phenylalanine+(2,5-dioxopyrrolidin-1-yl) 1,2,2,2-tetrachloroethyl carbonate→(2,5-dioxopyrrolidin-1-yl) 3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
L-phenylalanine→(2,5-dioxopyrrolidin-1-yl) 3-phenyl-2-(phenylmethoxycarbonylamino)propanoate

Precursor

Benzyl chloroformate
L-phenylalanine
N-Hydroxysuccinimide
(2,5-dioxopyrrolidin-1-yl) 1,2,2,2-tetrachloroethyl carbonate

Downstream Product

Cbz-L-Phenylalaninal
L-Phenylalanine methylamide
H-PHE-ARG-OH TRIFLUOROACETATE SALT
(S)-Cbz-Phenylalaninol

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