Home > Aromatic Compounds> Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid

Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid

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Origin: China

Cas No: 88050-17-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 88050-17-3 Formula: C20H19NO5 Molecular Weight: 353.36900

Basic Info

Chemical Name	Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid
Synonyms	(2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;
CAS No.	88050-17-3
Molecular Formula	C20H19NO5
Molecular Weight	353.36900
PSA	87.07000
LogP	2.39320

Properties

Appearance & Physical State	White to off-white crystalline powder
Density	1.407g/cm3
Boiling Point	595.5ºC at 760 mmHg
Melting Point	189-193ºC
Flash Point	314ºC
Refractive Index	1.658
Storage Condition	2-8ºC

Safety Info

Safety Statements	S22; S24/25
HS Code	2933990090

Synthesis Route

9H-fluoren-9-ylmethyl carbonochloridate+4-hydroxy-L-proline→Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid
N-(9-Fluorenylmethoxycarbonyloxy)succinimide→Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid
trimethylsilyl (2S,4R)-4-(trimethylsilyoxy)pyrrolidine-2-carboxylate→Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid

Precursor

9H-fluoren-9-ylmethyl carbonochloridate
4-hydroxy-L-proline
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
trimethylsilyl (2S,4R)-4-(trimethylsilyoxy)pyrrolidine-2-carboxylate

Downstream Product

1-O-(9H-fluoren-9-ylmethyl) 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
4-fluoropyrrolidine-2-carboxamide

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