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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Respiratory system> fexofenadine
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fexofenadine

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Origin: China

Cas No: 83799-24-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    83799-24-0
    Other Names:
    Fexofenadine
    MF:
    C32H39NO4
    EINECS No.:
    N/A
    Place of Origin:
    China
    Type:
    Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    99min%
    Brand Name:
    Milliflux
    Model Number:
    API
    Application:
    Pharmaceutical Raw Intermediates
    Appearance:
    N/A
    Packing:
    25kg/drum or 20kg/bag
    Assay:
    99.0 %min
    Storage:
    Room Temperature
    Shelf life:
    Proper Storage
    Grade:
    EP,USP,CP,JP
    Brand:
    Milliflux
    Website:
    www.milliflux.com
    Origin:
    China

    Packaging&Delivery

    Packaging Details
    Customer's request
    Port
    Any main port in china
    Lead Time:
    Quantity(Boxes)1 - 500>500
    Est. Time(days)7To be negotiated

  • Property

    CAS No.: 83799-24-0 Formula: C32H39NO4 Molecular Weight: 501.65600

    Description

    Fexofenadine (trade names Allegra, Fexidine, Telfast, Fastofen, Tilfur, Vifas, Telfexo, Allerfexo, Flexofen) is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Therapeutically, fexofenadine is a selective peripheral H1-blocker.
    Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines. It has also been called a third-generation antihistamine, although there is some controversy associated with the use of the term.
    Fexofenadine has been manufactured in generic form since 2011.

    Basic Info

    Chemical Name fexofenadine
    Synonyms

    Fexofenadine-D5;
    Fexafenadine;
    Fexofenadinebase;
    CARBOXYTERFENADINE;
    Fexofenadine;
    Terfenadine acid;
    TERFENADINECARBOXYLATE;

    CAS No. 83799-24-0
    Molecular Formula C32H39NO4
    Molecular Weight 501.65600
    PSA 81.00000
    LogP 5.44840

    Properties

    Appearance & Physical State white powder
    Density 1.171 g/cm3
    Boiling Point 697.3ºC at 760 mmHg
    Melting Point 218-220ºC
    Flash Point 375.5ºC
    Refractive Index 1.596

    Safety Info

    HS Code 2933399090

    Synthesis Route

    Fexofenadinone→fexofenadine
    Methyl 2-(4-(4-((4-((4-hydroxyphenyl)(phenyl)methyl)piperidin-1-yl)oxy)butyl)phenyl)-2-methylpropanoate→fexofenadine
    N-methoxy-N-methyl-2-(4-{1-hydroxy-4-[4-(hydroxy-diphenylmethyl)-piperidine-1-yl]-butyryl}-phenyl)-isobutyramide→fexofenadine

    Precursor

    Fexofenadinone
    2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1,1-dimethoxybutyl)phenyl)-2-methyl-propanoic acid
    N-methoxy-N-methyl-2-(4-{1-hydroxy-4-[4-(hydroxy-diphenylmethyl)-piperidine-1-yl]-butyryl}-phenyl)-isobutyramide
    Diphenyl(piperidin-4-yl)methanol

    Downstream Product

    FEXOFENADINE HYDROCHLORIDE

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