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fexofenadine

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начало: Китай

Кас Но: 83799-24-0

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 80 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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Характеристики продукции
Описание продукта

Quick Details
CAS No.:
83799-24-0
Other Names:
Fexofenadine
MF:
C32H39NO4
EINECS No.:
N/A
Place of Origin:
China
Type:
Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99min%
Brand Name:
Milliflux
Model Number:
API
Application:
Pharmaceutical Raw Intermediates
Appearance:
N/A
Packing:
25kg/drum or 20kg/bag
Assay:
99.0 %min
Storage:
Room Temperature
Shelf life:
Proper Storage
Grade:
EP,USP,CP,JP
Brand:
Milliflux
Website:
www.milliflux.com
Origin:
China
Packaging&Delivery
Packaging Details
Customer's request
Port
Any main port in china
Lead Time:
Quantity(Boxes) 1 - 500 >500
Est. Time(days) 7 To be negotiated

Property

CAS No.: 83799-24-0 Formula: C32H39NO4 Molecular Weight: 501.65600

Description

Fexofenadine (trade names Allegra, Fexidine, Telfast, Fastofen, Tilfur, Vifas, Telfexo, Allerfexo, Flexofen) is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Therapeutically, fexofenadine is a selective peripheral H1-blocker.
Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines. It has also been called a third-generation antihistamine, although there is some controversy associated with the use of the term.
Fexofenadine has been manufactured in generic form since 2011.

Basic Info

Chemical Name	fexofenadine
Synonyms	Fexofenadine-D5; Fexafenadine; Fexofenadinebase; CARBOXYTERFENADINE; Fexofenadine; Terfenadine acid; TERFENADINECARBOXYLATE;
CAS No.	83799-24-0
Molecular Formula	C32H39NO4
Molecular Weight	501.65600
PSA	81.00000
LogP	5.44840

Properties

Appearance & Physical State	white powder
Density	1.171 g/cm3
Boiling Point	697.3ºC at 760 mmHg
Melting Point	218-220ºC
Flash Point	375.5ºC
Refractive Index	1.596

Safety Info

HS Code	2933399090

Synthesis Route

Fexofenadinone→fexofenadine
Methyl 2-(4-(4-((4-((4-hydroxyphenyl)(phenyl)methyl)piperidin-1-yl)oxy)butyl)phenyl)-2-methylpropanoate→fexofenadine
N-methoxy-N-methyl-2-(4-{1-hydroxy-4-[4-(hydroxy-diphenylmethyl)-piperidine-1-yl]-butyryl}-phenyl)-isobutyramide→fexofenadine

Precursor

Fexofenadinone
2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1,1-dimethoxybutyl)phenyl)-2-methyl-propanoic acid
N-methoxy-N-methyl-2-(4-{1-hydroxy-4-[4-(hydroxy-diphenylmethyl)-piperidine-1-yl]-butyryl}-phenyl)-isobutyramide
Diphenyl(piperidin-4-yl)methanol

Downstream Product

FEXOFENADINE HYDROCHLORIDE

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