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Cortisone acetate

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Origin: China

Cas No: 50-04-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    50-04-4
    Other Names:
    Cortisone acetate
    MF:
    C23H30O6
    EINECS No.:
    200-006-5
    Type:
    Anti-Allergic Agents, Antibiotic and Antimicrobial Agents
    Grade Standard:
    Food Grade
    Usage:
    Animal Pharmaceuticals, Cortisone acetate powder for Medicine Grade
    Brand Name:
    DJ Hormones
    Model Number:
    Cortisone acetate powder
    Purity:
    Cortisone acetate 99% min
    Product name:
    Cortisone acetate powder
    Application:
    Cortisone acetate pills
    Color:
    White powder
    MOQ:
    10g
    Assay:
    HPLC 99%
    Storage:
    Cool Dried Storage
    Package:
    Aluminum Bag
    Shelf life:
    3 Years
    Delivery time:
    5-7days

    Packaging&Delivery

    Packaging Details
    25kgs packaging Fiber drum outside

    and plastic bag inside 1-25kgs packaging aluminium bag outside

    and double plastic bag inside
    Port
    HK port
    Lead Time:
    Quantity(Grams)1 - 1>1
    Est. Time(days)7To be negotiated

  • Property

    CAS No.: 50-04-4 Formula: C23H30O6 Molecular Weight: 402.48100

    Description

    Cortisone Acetate is a glucocorticoid. Cortisone Acetate is an antiinflammatory agent. Cortisone Acetate is bioavailable and readily converted to the therapeutically active form, Hydrocotisone.

    Basic Info

    Chemical Name Cortisone acetate
    Synonyms

    17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate;
    Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-;
    [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;
    Cortisone Acetate;
    21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione;
    4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate;

    CAS No. 50-04-4
    Molecular Formula C23H30O6
    Molecular Weight 402.48100
    PSA 97.74000
    LogP 2.56060

    Properties

    Appearance & Physical State solid
    Density 1.26g/cm3
    Boiling Point 577.3ºC at 760mmHg
    Melting Point 237-240ºC
    Flash Point 197.3ºC
    Refractive Index 1.566
    Stability Stable. Incompatible with strong oxidizing agents.

    Safety Info

    RTECS GM9140000
    Safety Statements S22-S36/37
    WGK Germany 3

    Synthesis Route

    21-acetoxy-17,20βF-dihydroxy-pregn-4-ene-3,11-dione+acetic acid→Cortisone acetate+Adrenosterone
    cortisol 21-acetate→11β-hydroxyandrost-4-ene-3,17-dione+Cortisone acetate
    [2-[(5R,8S,9S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate→Cortisone acetate

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal TDLo - Lowest published toxic dose Rodent - mouse 35 mg/kg 1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria
    2.Vascular-tumors
    3.Musculoskeletal-tumors
    Oral TDLo - Lowest published toxic dose Rodent - rat 300 mg/kg,female 20-21 day(s) after conception 1.Reproductive-Maternal Effects-parturition
    Oral TDLo - Lowest published toxic dose Rodent - rat 56 mg/kg,male 14 day(s) pre-mating 1.Reproductive-Paternal Effects-spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
    2.Reproductive-Paternal Effects-testes, epididymis, sperm duct
    3.Reproductive-Paternal Effects-prostate, seminal vesicle, Cowper's gland, accessory glands

    Precursor

    21-acetoxy-3,3-ethanediyldioxy-17-hydroxy-pregn-5-ene-11,20-dione
    cortisol 21-acetate
    [2-[(5R,8S,9S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
    cortisol

    Downstream Product

    [2-(6,17-dihydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] acetate
    Adrenosterone
    [2-[(8S,9S,10R,13S,14S,17R)-4-chloro-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
    cortancyl

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