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fludrocortisone acetate

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Origin: China

Cas No: 514-36-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 514-36-3 Formula: C23H31FO6 Molecular Weight: 422.48700

Description

A mineralocorticoid.

Basic Info

Chemical Name	fludrocortisone acetate
Synonyms	Fludrocortisone acetate;
CAS No.	514-36-3
Molecular Formula	C23H31FO6
Molecular Weight	422.48700
PSA	100.90000
LogP	2.44450

Properties

Appearance & Physical State	Crystalline solid
Density	1.3 g/cm3
Boiling Point	575.1ºC at 760 mmHg
Melting Point	233-234ºC
Flash Point	301.6ºC
Refractive Index	1.563
Storage Condition	-20ºC Freezer

Safety Info

RTECS	TU5050000
Safety Statements	22-26-36
HS Code	2937229000
WGK Germany	3
Risk Statements	R63
Hazard Codes	Xn

Synthesis Route

17-hydroxy-3,20-dioxo-9,11-epoxypregn-4-en-21-yl acetate→fludrocortisone acetate
11-Epicortisol→fludrocortisone acetate
[2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate→fludrocortisone acetate

Precursor

17-hydroxy-3,20-dioxo-9,11-epoxypregn-4-en-21-yl acetate
11-Epicortisol
[2-[(8S,9R,10S,13S,14S,17R)-9-bromo-11,17-dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
[2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Downstream Product

Isoflupredone Acetate
fludrocortisone
Isoflupredone

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