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chalcone

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Origin: China

Cas No: 94-41-7

Specification: 99%min

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 94-41-7 Formula: C15H12O Molecular Weight: 208.25500

    Description

    Chalcone is an aromatic ketone and an enone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones or chalconoids. Benzylideneacetophenone is the parent member of the chalcone series. The alternative name given to chalcone are phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone, ɣ-oxo-α,ɣ-diphenyl-α-propylene and α-phenyl-β-benzoylethylene.
    Chalcones and their derivatives demonstrate wide range of biological activities such as anti-diabetic, anti-neoplastic, anti-hypertensive, anti-retroviral, anti-inflammatory, anti-parasitic, anti-histaminic, anti-malarial, anti-oxidant, anti-fungal, anti-obesity, anti-platelet, anti-tubercular, immunosuppressant, anti-arrhythmic, hypnotic, anti-gout, anxiolytic, anti-spasmodic, anti-nociceptive, hypolipidemic, anti-filarial, anti-angiogenic, anti-protozoal, anti-bacterial, anti-steroidal, cardioprotective, etc.

    Basic Info

    Chemical Name chalcone
    Synonyms

    BENZALACETOPHENONE;
    benzylidene acetophenone;
    CHALKONE;
    Cinnamophenone;
    CHALCONE;
    PhCOCH=CHPh;
    styrylphenylketone;

    CAS No. 94-41-7
    Molecular Formula C15H12O
    Molecular Weight 208.25500
    PSA 17.07000
    LogP 3.58270

    Properties

    Appearance & Physical State light yellow powder
    Boiling Point 208 °C25 mm Hg(lit.)
    Melting Point 55-59 °C
    Flash Point >230 °F

    Safety Info

    RTECS UD5576750
    Safety Statements S22; S36/37/39; S45
    HS Code 2914399090
    WGK Germany 3
    Risk Statements R22; R36/37
    Hazard Codes Xn; Xi

    Synthesis Route

    dihydrochalcone→3-phenyl-1H-indene+trans-β-benzylstyrene
    N-benzyl-9H-fluoren-9-imine→cyclohexane-1,3-dione+chalcone
    →2,5-Diphenyloxazole+chalcone

    Precursor

    benzyl alcohol
    <i>trans</i>-1,3-Diphenyl-2-propen-1-ol
    benzaldehyde
    acetophenone

    Downstream Product

    4-hydroxy-3-(3-oxo-1,3-diphenylpropyl)chromen-2-one
    2-oxo-4-(2-phenylethenyl)chromene-3-carbonitrile
    2-Phenylacetophenone
    2,4-diphenyl-4H-pyrano[3,2-c]chromen-5-one

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