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cetrorelix

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Origin: China

Cas No: 120287-85-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    120287-85-6
    Other Names:
    Cetrorelix acetate
    MF:
    C70H92ClN17O14
    EINECS No.:
    1592732-453-0
    Place of Origin:
    Shandong, China
    Type:
    Peptide
    Purity:
    99%
    Brand Name:
    ENCH
    Model Number:
    ench-120287-85-6
    Application:
    Pharmaceuticals
    Appearance:
    White or light white power, White or light white power
    Color:
    White or light white
    Form:
    Power
    Melting point:
    n.a.
    Boiling point:
    n.a.
    Density:
    n.a.
    Molecular weight:
    1431.04
    Brand:
    ENCH
    Storage:
    -20°C
    Package:
    100g / package

    Packaging&Delivery

    Packaging Details
    1kg, 25kg,200kg/drum or 1kg, 5kg, 10kg, 25kg/bag or as your demands.
    Port
    Chinese main ports
    Lead Time:
    Quantity(Grams)1 - 10>10
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 120287-85-6 Formula: C70H92ClN17O14 Molecular Weight: 1431.04000

    Description

    Cetrorelix acetate (INN, USAN, BAN) (trade name Cetrotide) is an injectable gonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, it is used is used in assisted reproduction to inhibit premature luteinizing hormone surges The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In addition, cetrorelix can be used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). It is administered as either multiple 0.25mg daily subcutaneous injections or as a single-dose 3mg subcutaneous injection. The duration of the 3mg single dose is four days; if hCG is not administered within four days, a daily 0.25mg dose is started and continued until hCG is administered.

    Basic Info

    Chemical Name cetrorelix
    Synonyms

    CETRORELIX ACETATE(CETROTIDE);
    N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2;
    CETRORELIX;
    Cetrorelixum [inn-latin];
    Ac-DNal-DpCl-Phe-DPal-Ser-Tyr-DCit-Leu-Arg-Pro-D-Ala-NH2;
    Cetrorelixacetate;
    Ac-D-Nal-D-Cpa-D-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2;
    AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH;
    Cetrorelixum;
    CETRORELIX ACID;
    Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2;
    Unii-oon1hfz4ba;
    CETRIZINEDIHYDROCHLORIDE;
    Cetrorelix acetate;

    CAS No. 120287-85-6
    Molecular Formula C70H92ClN17O14
    Molecular Weight 1431.04000
    PSA 495.67000
    LogP 5.93230

    Properties

    Appearance & Physical State White powder
    Density 1.42g/cm3
    Refractive Index 1.667

    Synthesis Route

    BOC-L-Proline+N(α)-t-butoxycarbonyl-L-leucine→cetrorelix

    Precursor

    BOC-L-Proline
    N(α)-t-butoxycarbonyl-L-leucine
    2-((tert-Butoxycarbonyl)amino)propanoic acid
    Ornithine, N(2)-carboxy-N(5)-[(p-tolylsulfonyl)amidino]-, N(2)-tert-butyl ester, L-

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