Home > Chiral Compounds> Boc-trans-4-cyano-L-proline methyl ester

Boc-trans-4-cyano-L-proline methyl ester

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 194163-91-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 194163-91-2 Formula: C12H18N2O4 Molecular Weight: 254.28200

Basic Info

Chemical Name	Boc-trans-4-cyano-L-proline methyl ester
Synonyms	1-O-tert-butyl 2-O-methyl (2S,4R)-4-cyanopyrrolidine-1,2-dicarboxylate;
CAS No.	194163-91-2
Molecular Formula	C12H18N2O4
Molecular Weight	254.28200
PSA	79.63000
LogP	1.24648

Synthesis Route

4-hydroxy-L-proline→Boc-trans-4-cyano-L-proline methyl ester+1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
(2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride→Boc-trans-4-cyano-L-proline methyl ester+1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
N-Boc-trans-4-hydroxy-L-proline methyl ester hydrochloride→Boc-trans-4-cyano-L-proline methyl ester+1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate

Precursor

potassium cyanide
(2S,4S)-methyl 4-methanesulfonyloxy-N-Boc-pyrrolidine-2-carboxylate
4-hydroxy-L-proline
(2S,4R)-1-tert-Butyl 2-methyl 4-((methylsulfonyl)oxy)pyrrolidine-1,2-dicarboxylate

Hot tags: boc-trans-4-cyano-l-proline methyl ester, China, manufacturers, suppliers, factory, wholesale, low price, high quality