Home > Organic Nitrogen Compounds> 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone

6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone

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Origin: China

Cas No: 36725-28-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 36725-28-7 Formula: C11H11N3O Molecular Weight: 201.22500

Description

AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan, positive inotropic agent with vasodilating activity.

Basic Info

Chemical Name	6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone
Synonyms	6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone; 6-(4-Aminophenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one; 6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one;
CAS No.	36725-28-7
Molecular Formula	C11H11N3O
Molecular Weight	201.22500
PSA	71.77000
LogP	1.90870

Properties

Density	1.3 g/cm3
Refractive Index	1.652

Safety Info

HS Code	2933990090

Synthesis Route

(4S)-3-(4-aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one→6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone
4-(4-Aminophenyl)-3-methyl-4-oxobutanoic acid hydrochloride→6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone
diethyl 2-[1-(4-acetamidophenyl)-1-oxopropan-2-yl]propanedioate→6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-3(2H)-Pyridazinone

Precursor

diethyl 2-[1-(4-acetamidophenyl)-1-oxopropan-2-yl]propanedioate
4-(4-Aminophenyl)-3-methyl-4-oxobutanoic acid hydrochloride
methyl 3-(4-acetamidobenzoyl)but-3-enoate
4-(4-acetamidophenyl)-4-oxobutanoic acid

Downstream Product

levosimendan
4-methyl-3-[4-(4-oxopyridin-1-yl)phenyl]-4,5-dihydro-1H-pyridazin-6-one
Simendan
Metsulfuron

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