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6-Methyl-3(2H)-Pyridazinone

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Origin: China

Cas No: 13327-27-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 13327-27-0 Formula: C5H6N2O Molecular Weight: 110.11400

Description

6-Methyl-3-pyridazinone is a lignin-based dye used on wool. 6-Methyl-3-pyridazinone is also used as a reactant for the synthesis of C-(1-aryl-cyclohexyl)-methylamine derivatives as selective, orally available inhibitors of dipeptidyl peptidase IV, imidazopyridazinone derivatives as PDE7 inhibitors and pyridazinone derivatives with an arylpiperazinylalkyl chain as a potentent, orally active, antinociceptive agent.

Basic Info

Chemical Name	6-Methyl-3(2H)-Pyridazinone
Synonyms	3-methyl-1H-pyridazin-6-one; 6-Methylpyridazin-3(2H)-one; 3-Hydroxy-6-methylpyridazine; 6-Methyl-3(2H)-pyridazinone; 6-methyl-3-pyridazinone;
CAS No.	13327-27-0
Molecular Formula	C5H6N2O
Molecular Weight	110.11400
PSA	45.75000
LogP	0.07830

Properties

Appearance & Physical State	colorless crystals
Density	1.22 g/cm3
Boiling Point	310.3ºC at 760 mmHg
Melting Point	143-145ºC
Flash Point	141.5ºC
Refractive Index	1.576
Vapor Pressure	0.000331mmHg at 25°C

Safety Info

Safety Statements	S26-S36
HS Code	2933990090
Risk Statements	R36/37/38

Synthesis Route

4,5-Dihydro-6-methylpyridazin-3(2H)-one→6-Methyl-3(2H)-Pyridazinone
N'-acryloyl-N-(but-3-en-2-yl)-4-methylbenzenesulfonohydrazide→6-Methyl-3(2H)-Pyridazinone
→6-Methyl-3(2H)-Pyridazinone

Precursor

3-Chloro-6-methylpyridazine
4,5-Dihydro-6-methylpyridazin-3(2H)-one
2-t-butyl-2,3-dihydro-6-methyl-3-oxopyridazine-4-carboxylic acid
N'-acryloyl-N-(but-3-en-2-yl)-4-methylbenzenesulfonohydrazide

Downstream Product

3-Bromo-6-methylpyridazine
6-Hydroxy-3-pyridazinecarboxylic Acid
6-Chloropyridazine-3-carboxylic acid
6-Chloro-Pyridazine-3-Carboxylic Acid Ethyl Ester

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