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5-formylpyridine-2-carbonitrile

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Origin: China

Cas No: 131747-68-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 131747-68-7 Formula: C7H4N2O Molecular Weight: 132.11900

Description

6-Cyanopyridine-3-carboxaldehyde, is an intermediate used for the synthesis of pharmaceutical compounds, such as GLPG0634, which is used for treatment of rheumatoid arthritis

Basic Info

Chemical Name	5-formylpyridine-2-carbonitrile
Synonyms	6-cyanonicotinaldehyde; 5-Formylpicolinonitrile; 6-cyano-pyridine-3-carbaldehyde; 5-FORMYL-2-PYRIDINECARBONITRILE;
CAS No.	131747-68-7
Molecular Formula	C7H4N2O
Molecular Weight	132.11900
PSA	53.75000
LogP	0.76578

Safety Info

HS Code	2933399090

Synthesis Route

5-(hydroxymethyl)pyridine-2-carbonitrile→5-formylpyridine-2-carbonitrile
5-(1,3-dioxolan-2-yl)pyridine-2-carbonitrile→5-formylpyridine-2-carbonitrile
Oxalyl Chloride+5-(hydroxymethyl)pyridine-2-carbonitrile→5-formylpyridine-2-carbonitrile

Precursor

5-(1,3-dioxolan-2-yl)pyridine-2-carbonitrile
Oxalyl Chloride
5-(hydroxymethyl)pyridine-2-carbonitrile
(6-cyanopyridin-3-yl)methyl acetate

Downstream Product

5-(Difluoromethyl)-2-pyridinecarboxylic acid

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