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5-[(1S,3S,4R)-7-azabicyclo[2.2.1]heptan-3-yl]-3-methyl-1,2-oxazole

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Origin: China

Cas No: 188895-96-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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    CAS No.: 188895-96-7 Formula: C10H15ClN2O Molecular Weight: 214.69200

    Description

    Epiboxidine is a chemical compound which acts as a partial agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. It was developed as a less toxic analogue of the potent frog-derived alkaloid epibatidine, which is around 200 times stronger than morphine as an analgesic but produces extremely dangerous toxic side effects.
    Epiboxidine is around one-tenth as potent as epibatidine as an α4β2 agonist, but has around the same potency as an α3β4 agonist. It has only one-tenth of the analgesic power of epibatidine, but is also much less toxic.

    Basic Info

    Chemical Name 5-[(1S,3S,4R)-7-azabicyclo[2.2.1]heptan-3-yl]-3-methyl-1,2-oxazole
    Synonyms

    (+-)-Epiboxidine;
    exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo(2.2.1)heptane;
    7-Azabicyclo(2.2.1)heptane,2-(3-methyl-5-isoxazolyl)-,exo;

    CAS No. 188895-96-7
    Molecular Formula C10H15ClN2O
    Molecular Weight 214.69200
    PSA 38.06000
    LogP 2.72170

    Properties

    Density 1.13g/cm3
    Boiling Point 313.1ºC at 760mmHg
    Flash Point 143.2ºC
    Refractive Index 1.53
    Storage Condition -20ºC
    Vapor Pressure 0.000507mmHg at 25°C

    Safety Info

    RTECS CL5446415
    Safety Statements S22; S24/25
    WGK Germany 3

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