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Home > Aminoacid Compounds> (3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Picture of (3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

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FOB Price $295.10

Origin: China

Cas No: 128502-56-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 128502-56-7 Formula: C10H11NO3 Molecular Weight: 193.19900

    Description

    L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid is a possible histone deacetylases (HDACs) inhibitor. It is used in the design of boronic acid-based autotaxin inhibitors.

    Basic Info

    Chemical Name (3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
    Synonyms

    1,2,3,4,-tetrahydro-7-hydroxyisoquinoline-3-carboxylic acid;
    L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid;
    H-Tic(OH)-OH;

    CAS No. 128502-56-7
    Molecular Formula C10H11NO3
    Molecular Weight 193.19900
    PSA 69.56000
    LogP 0.81990

    Properties

    Appearance & Physical State Yellow crystalline powder
    Density 1.351 g/cm3
    Boiling Point 456.3ºC at 760 mmHg
    Melting Point 336 - 338ºC
    Flash Point 229.8ºC
    Refractive Index 1.612
    Storage Condition 2-8ºC
    Vapor Pressure 4.06E-09mmHg at 25°C

    Safety Info

    Safety Statements S24/25
    HS Code 2933499090

    Synthesis Route

    (S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid→(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
    3,5-diiodo-L-tyrosine→(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

    Precursor

    3,5-diiodo-L-tyrosine
    (S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid

    Downstream Product

    Boc-7-hydroxy-(S)-1,2,3,4-tetrahydroisoquinoline-3 -carboxylic acid

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