Início > Aminoacid Compounds> (3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

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Origem: China

Cas No: 128502-56-7

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

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CAS No.: 128502-56-7 Formula: C10H11NO3 Molecular Weight: 193.19900

Description

L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid is a possible histone deacetylases (HDACs) inhibitor. It is used in the design of boronic acid-based autotaxin inhibitors.

Basic Info

Chemical Name	(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Synonyms	1,2,3,4,-tetrahydro-7-hydroxyisoquinoline-3-carboxylic acid; L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; H-Tic(OH)-OH;
CAS No.	128502-56-7
Molecular Formula	C10H11NO3
Molecular Weight	193.19900
PSA	69.56000
LogP	0.81990

Properties

Appearance & Physical State	Yellow crystalline powder
Density	1.351 g/cm3
Boiling Point	456.3ºC at 760 mmHg
Melting Point	336 - 338ºC
Flash Point	229.8ºC
Refractive Index	1.612
Storage Condition	2-8ºC
Vapor Pressure	4.06E-09mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2933499090

Synthesis Route

(S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid→(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
3,5-diiodo-L-tyrosine→(3S)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

Precursor

3,5-diiodo-L-tyrosine
(S)-1,2,3,4-Tetrahydro-7-hydroxy-6,8-diiodoisoquinoline-3-carboxylic acid

Downstream Product

Boc-7-hydroxy-(S)-1,2,3,4-tetrahydroisoquinoline-3 -carboxylic acid

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