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1-aminocyclopentanecarboxylic acid

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начало: Китай

Кас Но: 52-52-8

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 100 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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Характеристики продукции
Описание продукта

Quick Details
CAS No.:
52-52-8
Other Names:
Cycloleucine
MF:
C6H11NO2
EINECS No.:
200-144-6
Place of Origin:
Shanghai, China
Grade Standard:
Agriculture Grade, Electron Grade, Food Grade, Industrial Grade, Medicine Grade, Reagent Grade
Purity:
99%
Appearance:
White Powder
Application:
Medicine
Brand Name:
Terppon
Model Number:
9
color:
White
Packaging&Delivery
Packaging Details
DRUMS
Port
Shanghai
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 20 To be negotiated

Property

CAS No.: 52-52-8 Formula: C6H11NO2 Molecular Weight: 129.15700

Description

Cycloleucine is a non-proteinogenic amino acid. It could be classified as a cyclic derivate of norleucine, having two hydrogen atoms less. Leading structure is a cyclopentane-ring. The α-carbon atom is not a stereocenter.
Cycloleucine is a non-metabolisable amino acid and is a specific and reversible inhibitor of nucleic acid methylation, and as such is widely used in biochemical experiments.

Basic Info

Chemical Name	1-aminocyclopentanecarboxylic acid
Synonyms	1-Aminocyclopropane-1-carboxylic acid?; 1-Aminocyclopentanecarboxylic acid; 1-amino-1-carboxycyclopentane; 1-amino-1-cyclopentanecarboxylic acid; 1-aminocyclopentane-1-carboxylic acid; Cycloleucine; 1-Aminocyclopropane-1-carboxylic acid; Cyclolencine; Cyclopentanecarboxylic acid, 1-amino-; 1-Aminocyclopentanecarboxylicacid; 1-amino-1-carboxylic cyclopentane;
CAS No.	52-52-8
Molecular Formula	C6H11NO2
Molecular Weight	129.15700
PSA	63.32000
LogP	1.04280

Properties

Appearance & Physical State	white to beige crystalline powder
Density	1.207 g/cm3
Boiling Point	256.1ºC at 760 mmHg
Melting Point	320-322ºC
Flash Point	108.7ºC
Refractive Index	1.522
Water Solubility	5 g/100 mL
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at RT.

Safety Info

RTECS	GY2625000
Hazard Class	6.1
Safety Statements	S22-S24/25
HS Code	2922499990
WGK Germany	3
Packing Group	III
RIDADR	UN 2811
Risk Statements	R22
Hazard Codes	Xn
Hazard Declaration	H301
Symbol	GHS06
Caution Statement	P301 + P310
Signal Word	Danger

Synthesis Route

1,3-Diazaspiro[4.4]nonane-2,4-dione→1-aminocyclopentanecarboxylic acid
cyclopentanone→1-aminocyclopentanecarboxylic acid
1-(hydroxyamino)cyclopentane-1-carboxylic acid→1-aminocyclopentanecarboxylic acid

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Human	60 mg/kg	1.Behavioral-anorexia (human) 2.Gastrointestinal-nausea or vomiting
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	290 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	340 mg/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

1,3-Diazaspiro[4.4]nonane-2,4-dione
cyclopentanone
CYCLOPENTANONE OXIME
1-(hydroxyamino)cyclopentane-1-carboxylic acid

Downstream Product

N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-1-[(1-oxopentyl)amino]cyclopentanecarboxamide
6,9-diazaspiro[4.5]decane,dihydrochloride
Cyclopentanecarboxylic acid
7,14-diazadispiro[4.2.4<sup>8</sup>.2<sup>5</sup>]tetradecane-6,13-dione

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