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3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one

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Origin: China

Cas No: 82543-16-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
82543-16-6
Other Names:
Drospirenone intermediate Q5
MF:
C21H30O3
EINECS No.:
617-347-4
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
98%MIN
Brand Name:
Royal pharm
Model Number:
Drospirenone intermediate Q5
Application:
Used
Appearance:
solid
MW:
330.46
Packaging&Delivery
Packaging Details
Drum&plastic bags or Aluninium foiled bag&zip lock bag
Port
HangZhou
Lead Time:
Quantity(Grams) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 82543-16-6 Formula: C21H30O3 Molecular Weight: 330.46100

Description

Intermediate of Drospirenone.

Basic Info

Chemical Name	3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one
Synonyms	6,7,15,16-Dimethylene-3,5-dihydroxyandrostan-17-one; 3,5-DIHYDROXY-6,7:15,16-DIMETHYLENE-5-ANDROSTAN-17-ONE; 6,7,15,16 dimethylen 3,5,dihydroxy androstan 17 dion; 6b,7b,15b,16b-Dimethylene-3b,5b-dihydroxyandrostan-17-one;
CAS No.	82543-16-6
Molecular Formula	C21H30O3
Molecular Weight	330.46100
PSA	57.53000
LogP	2.78580

Properties

Appearance & Physical State	white solid
Density	1.205g/cm3
Boiling Point	476.6ºC at 760 mmHg
Melting Point	205-207ºC
Flash Point	256.2ºC
Refractive Index	1.583

Synthesis Route

3β,5β-Dihydroxy-15β,16β-methylene-androst-6-en-17-one+dibromomethane→3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one
Diiodomethane+3β,5β-Dihydroxy-15β,16β-methylene-androst-6-en-17-one→3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one
15β,16β-methylenedehydroepiandrosterone→3b,5-Dihydroxy-6b,7b:15b,16b-dimethylene-5b-androstan-17-one

Precursor

Diiodomethane
dibromomethane
3β,5β-Dihydroxy-15β,16β-methylene-androst-6-en-17-one
15β,16β-methylenedehydroepiandrosterone

Downstream Product

spirorenone
17α-(3-hydroxy-1-propinyl)-6β,7β,15β,16β-dimethylene-5β-androstane-3β,5,17β-triol

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